Perimenopausal changes and changes related to hormone replacement therapy mimic ASCUS
, which lead to false positive diagnosis of ASCUS
in older women.
Patologia cervical y el reporte de ASCUS
en la citologia cervical.
Walker J, Wang S, Schiffman M, Solomon D, ASCUS
LSIL Triage Study Group.
The authors noted that their finding of increased ASCUS
detection among HIV-positive women clashed with results from a previous investigation, in which ASCUS
incidence did not vary significantly by HIV status.
The normal parabasal cell nuclei, on an average, were larger (2211 pixels) than nuclei of ASCUS
(1866 pixels) and LSIL (1784 pixels) but they were more uniform with lesser variation (SD: 382 vs.
HPV DNA testing is being increasingly adopted as a clinical management tool in women with ASCUS
Guido R, Schiffman M, Solomon D, Burke L; ASCUS
LSIL Triage Study (ALTS) Group.
Materiales y metodos: estudio de corte transversal entre febrero del 2003 y abril del 2005, en mujeres con diagnostico citologico de ASCUS
, en el Hospital Universitario de la Samaritana.
Data from other studies (19-21) on further evaluation of ASCUS
(atypical squamous cells of unknown significance) findings demonstrate a cervical intra-epithelial neoplasia (CIN)-1 rate of 10 - 20% and a CIN-2 and CIN-3 rate of 3 - 5%.
Comparison of management strategies for women diagnosed as CIN 1 or less postcolposcopic evaluation: data from the ASCUS
and LSIL triage study (ALTS), a multicenter randomized trial.
6%) said they used it for ASCUS
Pap test results as recommended.
By the follow-up exam, (mean 11 months later) 65% of LSIL, 67% of ASCUS
, 57% of ASC-H, and 55% of HSIL had regressed.
A study published in a recent issue of the Journal of the National Cancer Institute (February 2001;93(4):293-299) looked at more than 3,000 women with ASCUS
results over a 2-year period.
Negative predictive value is the probability that there is no cervical disease in a patient with atypical or ASCUS
Pap test results and negative HPV test results.
Sexually transmitted infection have been considered as possible factors in the pathogenesis of cervical epithelial lesions such as ASCUS
, Low grade squamous intraepithelial lesion (LSIL) and High grade squamous intraepithelial lesion (HSIL).