A forty-seven-year-old man had a history of recurrent oral aphthae
and genital ulceration, anterior uveitis, and erythema nodosum that led to a diagnosis of BD 15 years ago.
Ferguson MM, McKay Hart D, Lindsay R et al: Progestin therapy for menstrual related aphthae
, pseudowarts, and infantile labial agglutination are nearly unique to girls, she said.
She had a combination of minor and major aphthae
growing in her mouth.
The significant findings included ulcers and erosions in 36%, erythema in 22%, aphthae
in 17%, nodular lymphoid hyperplasia in 20%, and other features in 5%.
In October 2001, she developed fatigue, fever, anorexia, and painful oral and vaginal aphthae
and skin pustules, along with erythematous tender subcutaneous nodules of the lower extremities consistent with erythema nodosum.
He initially had recurrent painful oral aphthae
and subsequently developed severe granulomatous colitis with extraintestinal involvement of the perianal tissues and the esophagus.
He described recurrent oral aphthae
, genital ulcers, and visual blurring.