compound

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Related to antisense compound: Antisense therapy, antisense DNA
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Synonyms for compound

Synonyms for compound

consisting of two or more interconnected parts

Synonyms for compound

a whole formed by a union of two or more elements or parts

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(chemistry) a substance formed by chemical union of two or more elements or ingredients in definite proportion by weight

an enclosure of residences and other building (especially in the Orient)

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make more intense, stronger, or more marked

put or add together

calculate principal and interest

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create by mixing or combining

composed of more than one part

consisting of two or more substances or ingredients or elements or parts

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composed of many distinct individuals united to form a whole or colony

References in periodicals archive ?
Thus, without changing their core chemistry group, companies like Isis can switch from an antisense compound that battles CMV to one that attacks the wart-causing strains of human papillomavirus.
The resulting antisense compounds shut down the cellular factory churning out a disease-causing protein.
Although researchers have been conducting laboratory and animal tests of antisense compounds for about a decade, clinical data are just starting to roll in at scientific meetings.
Antisense compounds intervene before a disease-associated protein is ever produced (SN: 2/16/91, p.
Molecular biologists believe that antisense compounds may improve these grim realities of AIDS treatment.
Such results raise the possibility that antisense compounds will keep HIV at bay, perhaps long enough to be considered a virtual cure.
Patent 5,543,507, "Covalently Cross-Linked Oligonucleotides," covers antisense compounds with tethers which stabilize the secondary structure of antisense compounds, allowing them to mimic natural nucleic structures, such as stem loops, which are believed to be important in RNA/protein interactions.
Patent 5,554,746, "Synthesis of Lactam Nucleic Acids," covers applications of monomeric units for synthesis of antisense compounds whose building units incorporate a cyclic lactam structure that is found in many antibiotics.
Isis is currently testing antisense compounds containing the novel oligonucleosides described in the patent.
NASDAQ: ISIP), describes studies of novel antisense compounds in living cancer cells against the Ha-ras oncogene known to be active in a wide range of human cancers.
In the 1992 publication, the Isis team described antisense compounds consisting of phosphorothioate oligonucleotides, which specifically inhibited expression of the cancer-causing mutant ras gene.
In today's publication, Monia and his collaborators describe antisense compounds against Ha-ras which take advantage of second- generation oligonucleotide chemistries under development at Isis.
Antisense compounds have been designed to inhibit the translation of DNA or RNA into proteins that perform functions within a living cell.