Group-5: Antibiotic, antifungal, and antiprotozoal drugs
The present study was designed to investigate the incidence of Trypanosomiasis and observe the efficacy of antiprotozoal drugs
for the treatment of Trypanosomiasis in Thari camels.
Certain molecules isolated from natural sources represent a major breakthrough in the search for new antiprotozoal drugs
, since there is urgent need for a new era of innovative medicines (Rocha et at.
Natural products and development of selective antiprotozoal drugs
Although antiprotozoal drugs
can treat babesiosis, an uncontrolled infection can kill a dog within four days.
Among giardiasis patients, nitroimidazole treatment failure is often associated with failure of antiprotozoal drugs
in additional classes and with patient immunoglobulin deficiency.
In this context, the compounds (-) mammea A/BB (1) and 5,7-dihydroxy-8-(2-methylbutanoy1)-6-(3-methylbuty1)-4-phenyl-chroman-2-one (3) are potential candidates for further research to develop new antiprotozoal drugs
, considering their significant antileishmanial activity that may act in depolarization of the mitochondria] membrane potential cells, leading to death of the parasite.
Research on antiprotozoal drugs
of medicinal plant origin is a multidisciplinary task which involves researchers and students in the fields of botanics, phytochemistry, parasitology, pharmacology and medicine (Billo et al.
Natural products as sources of antiprotozoal drugs