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Related to antimalarial: Antimalarial Drugs
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Thus, a plant extract manifesting a plethora of antimalarial disease activities will prove to be very useful to reduce disease complications.
These compounds are believed to be unique as they have a mechanism of action inhibiting protein synthesis, which is completely different to other existing antimalarial medicines.
Currently in all endemic and non-endemic provinces, artemether-lumefantrine (AL) is the recommended first-line antimalarial medicine for the treatment of uncomplicated falciparum malaria.
Using the dried whole plant instead of purified artemisinin could significantly lower the cost of treating malaria, because it would eliminate the need to extract the drug from the plant and purify it, and could greatly expand access to antimalarial therapy, according to Pamela Weathers, professor of biology and biotechnology at WPI and a co-author of the new study.
This is true of the most important antimalarial natural products revealed to date: quinine (isolated from the bark of Cinchona spp.
The other important lesson from the study is about combination antimalarial therapy.
The study, published May 21 in Lancet Infectious Diseases, estimated 36 percent of antimalarial drugs analyzed in Southeast Asia were fake.
Poor quality antimalarial drugs lead to drug resistance and inadequate treatment that pose an urgent threat to vulnerable populations, according to a National Institutes of Health study published May 22 in The Lancet Infectious Diseasesjournal.
No adverse effects related to antimalarial treatment were observed, even with artesunate, which is currently not recommended for pregnant women.
With failure rates ranging between 50 to 95% reported for chloroquine in parts of Nigeria (Falade et al, 2005; FMOH, 2004) and resistance to the classical antimalarial drugs, notably--chloroquine, sulfadoxine-pyrimethamine, mefloquine, quinine been well documented (White, 1992; Krogstad, 1996).
AdvaCare, already having a strong presence in countries throughout Africa, Asia, the Middle East and South America, is now introducing its Pharmaceutical, Antimalarial, Oncology, Veterinary and Medical Supplies products into new markets.
Summary: TEHRAN (FNA)- An international team of scientists discovered a family of chemical compounds that could lead to a new generation of antimalarial drugs capable of not only alleviating symptoms but also preventing the deadly disease.
Two weeks prior, she had returned from a 1-month stay in the Comoros archipelago (islands situated to the east of Mozambique), during which she had not taken antimalarial prophylaxis.
In affected areas you need to use mosquito nets and insect repellents to avoid being bitten and take antimalarial medicines.
To the Editor: Resistance of Plasmodiumfalciparum to antimalarial drugs is one of the most worrying problems in tropical medicine.