Oral antihypertensive drugs
, lifestyle modification including exercise and dietary modification are milestones for hypertension therapy (Chobanian et al.
Major Finding: The risk of hip fracture within 45 days of starting an antihypertensive drug
increased by 43% in elderly patients (incidence rate ratio, 1.
Four-year persistence patterns among patients initiating therapy with the angiotensin II receptor antagonist losartan versus other antihypertensive drug
Participants in the parent study had to have a diastolic blood pressure >90 mmHg after discontinuing antihypertensive drug
Benefits of antihypertensive drugs
for mild hypertension are unclear [online article summary].
Ninety-one patients with previous diagnosis of hypertension and already taking antihypertensive drugs
were included in the study We further subdivided these patients into "uncontrolled" (Group A, n=44, mean age: 48 [+ or -] 10years, male/female ratio: 26/18) and controlled groups (Group B, n=47, mean age: 51 [+ or -] 13 years, male/female ratio: 29/18) according to whether their average 24-hour blood pressure value is higher (uncontrolled group) or lower (controlled) than 135\85 mmHg.
therapy in our study population consisted of angiotensin-converting enzyme inhibitors (A) and angiotensin II receptor blockers, beta-blockers (B), calcium channel blockers (C) and diuretics (D) used as single drug therapy or in various combinations.
Information collected from the chart included patient demographics, nurses' neurologic assessments for extremity strength, systolic blood pressure (SBP) and diastolic blood pressure (DBP) measurements at hospital admission and for 96 hours following admission, antihypertensive drug
use before and during hospitalization, and mortality.
This study addresses a high priority research need recognized in a 2011 Agency for Healthcare Research and Quality (AHRQ) comparative effectiveness review, which identified a gap in observational research examining differences in longitudinal adherence rates across the different RAS antihypertensive drug
Differences in glucose tolerance between fixed-dose antihypertensive drug
combinations in people with metabolic syndrome.
Optimal first-step antihypertensive drug
therapy in persons with type 2 diabetes mellitus (DM) or impaired fasting glucose (IFG) is uncertain.
This new research has been documented in a report titled Effects of Initial Antihypertensive Drug
Class on Patient Persistence and Compliance in a Usual-Care Setting in the U.
accelerated significantly after the introduction of tolerable antihypertensive drug
therapy in the 1960s," they wrote.
They obtained long-term mortality data for participants in the Systolic Hypertension in the Elderly Program (SHEP) trial, which was a randomised, placebo-controlled, clinical trial designed to assess the effect of antihypertensive drug
treatment (chlorthalidone) in reducing the risk of stroke in patients with isolated systolic hypertension.
Analysis of revenue and volume sales of antihypertensive drug
classes in the seven major markets* Assess the impact of key patent expiries, such as Merck & Co's Cozaar and Hyzaar* Forecast antihypertensive revenue and volume sales to 2019, including performance of developmental agents* Understand the impact of clinical trials and pipeline agents on future market dynamics