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aurantifolia Swingle fruits known as lime showed the most broad antibacterial spectrum with the strong antioxidant activity specially in methanol extracts.
It has a wide antibacterial spectrum and is also effective against PRSP (penicillin-resistant Streptococcus pneumoniae) and MRSA (methicillin-resistant Staphylococcus aureus), which have been reported to present major medical problems in recent years due to their resistance to conventional drugs.
According to Jack, et al (4), bacteriocins are "ribosomally synthesized peptides of 30 to less than 60 amino acids, with a narrow to wide antibacterial spectrum against Gram-positive bacteria; the antibacterial property is heat stable, and a producer strain displays a degree of specific self-protection against its own antibacterial peptide.
The two primary advantages of ciprofloxacin drops, and ofloxacin drops as well, are their lack of ototoxicity and their broad antibacterial spectrum.
The unique antibacterial spectrum of nematophin may indicate a novel mode of action, and thus may lead to new targets for the control of Staphylococcus infection.
Using these, the team is able to leverage previously unexploited portions of the ribosome to engineer macrolides that overcome resistance, extend antibacterial spectrum and drive oral efficacy in animal models of infection.
By applying designer modifications to validated antibiotics, MicuRx intends to improve overall pharmacological properties of antimicrobial drugs in order to overcome antibiotic resistance, increase the antibacterial spectrum, improve the dosing regimen, or reduce adverse side effects.