Physicians' antibiotic choices in the cohort of patients whose antibiotic regimens were not consistent with the South African guidelines (N = 168) Number of Antibiotic choice patients % IV 2nd-generation cephalosporin [+ or -] fluoroquinolone 86 51 IV penicillin G [+ or -] fluoroquinolone/ chloramphenicol/aminoglycoside 38 23 IV amoxicillin-clavulanic acid
[+ or -] fluoroquinolone 29 17 IV 3rd-generation cephalosporin [+ or -] IV flucloxacillin 8 5 Oral amoxicillin/erythromycin [+ or -] metronidazole 5 3 IV piperacillin and aminoglycoside/fluoroquinolone 2 1 IV = intravenous.
Patients with AECB (1,245) were treated with telithromycin 800 mg once daily for five days, amoxicillin-clavulanic acid
500/125 mg three times daily for 10 days, or cefuroxime axetil 500 mg twice daily for 10 days.
(AMC) is one of the most consumed antimicrobial agents in many countries (4-6), principally for respiratory and urinary tract infections.
All isolates were tested for susceptibility to ampicillin, amoxicillin-clavulanic acid
, cefoxitin, ceftriaxone, cephalothin, chloramphenicol, ciprofloxacin, gentamicin, kanamycin, nalidixic acid, streptomycin, sulfisoxazole, tetracycline, and trimethoprim-sulfamethoxazole, by using the Kirby-Bauer disk diffusion method.
She treated herself with amoxicillin-clavulanic acid
2 gm/day for 3 days.
In addition, both strains were found to be d-tartrate-fermenting (dT+) biovars (4), susceptible to ampicillin, amoxicillin-clavulanic acid
, cephalothin, ceftazidime, gentamicin, streptomycin, chloramphenicol, tetracycline, neomycin, nalidixic acid, norfloxacin, and ciprofloxacin and resistant to sulfamethoxazole and co-trimoxazole.
Antimicrobial drug susceptibility was performed with broth microdilution according to the Sensititre user manual and National Committee for Clinical Laboratory Standards (NCCLS) guidelines (7) for amikacin, amoxicillin-clavulanic acid
, ampicillin, cefazolin, ceftiofur, ceftizoxime, chloramphenicol, enrofloxacin, gentamicin, tetracycline, ticarcillin-clavulanic acid, and trimethoprim-sulfamethoxazole.
After the second operation, she had been treated for a local scar infection with amoxicillin-clavulanic acid
for 1 week.
Integron- and carbenicillinase-mediated reduced susceptibility to amoxicillin-clavulanic acid
in isolates of multidrug-resistant Salmonella enterica serotype Typhimurium DT104 from French patients.
22), nor previous antibiotic treatment (amoxicillin, amoxicillin-clavulanic acid
, extended-spectrum cephalosporins, and fluoroquinolones [p = 1.
Typhimurium isolates demonstrated the highest level of resistance were sulfamethoxazole (53%), streptomycin (51%), tetracycline (50%), ampicillin (48%), chloramphenicol (35%), kanamycin (16%), amoxicillin-clavulanic acid
(5%), cephalothin (5%), gentamicin (4%), trimethoprim-sulfamethoxazole (4%), ceftiofur (2%), ceftriaxone (1%), and nalidixic acid (1%).