Reaching a peak at days 4 to 5, hyaline membranes are composed of plasma proteins and cellular debris gathered into dense, glassy eosinophilic membranes found along alveolar septa with accentuation in alveolar ducts
ResultsIn the control group, normal alveolar duct
, alveolar spaces and terminal bronchioles with regular size and shape of the alveoli were found (Figure-1).
2]-NB-exposed mice show inflammatory lesions primarily localized to alveolar duct
3] exposure and remodeling of the distal airways, including an increase in nonciliated cell mass and volume fraction in terminal bronchioles and bronchiolarization of the alveolar duct
(Plopper et al.
Hyperinflation and linear markings are radiologic evidence of bronchiolar, peribronchiolar, and/or alveolar duct
inflammation (Calderon-Garciduenas et al.
Septum of alveolar duct
or alveolus Including septa of alveolar outpocketings of respiratory bronchioles in humans 9.
Some cases of organizing DAD may, however, contain comparatively prominent intraalveolar or alveolar duct
fibrosis and therefore, OP may arise in the histologic differential diagnosis.
6 mm within the walls of respiratory bronchioles and adjacent alveoli; nodules, defined as fibrotic lesions up to 1 cm in size with round, irregular, or serpiginous borders and containing dust-laden macrophages; and interstitial fibrosis, defined as diffuse or irregular fibrosis of alveolar septa and/or alveolar ducts
In diffuse lung adenocarcinoma, cancer cells usually grow invasively along alveolar and alveolar ducts
, spread along the lymphatic vessels, or metastasis to bilateral lungs by the way of lymph and blood.
Lung parenchyma showed marked congestion and thickening of the alveolar septa by fibrosis (Figure 1) accompanied by loose plugs of proliferating fibroblasts within the alveolar ducts
and airspaces (Figures 2-4).
Organizing pneumonia (OP) is characterized by plugs of collagen and fibroblasts that fill respiratory bronchioles, alveolar ducts
and alveoli (Figure 3).
interstitial edema, hyaline membrane lining alveolar ducts
& alveolar spaces, marked alveolar capillary congestion) such type of metastatic deposits also noticed in heart & brain.
After the EHF-therapy treating mice of the 3rd Group the alveolar ducts
of tubular glands were lined with stratified prismatic epithelium.
the terminal bronchioles, alveolar ducts
, and alveolar sacs.
Organizing pneumonia is diagnosed by its histopathologic pattern of fibroblastic plugs within alveolar ducts
and inflammatory changes in the surrounding alveoli with varied bronchiolar involvement.