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As a result of the promising work published in Cytotherapy, the University of Minnesota and BioE recently entered into a joint research collaboration to further evaluate the use of the MLPC for creating airway epithelial cells, such as type II alveolar cells, that could aid in combating diseases such as emphysema and cystic fibrosis, as well as pulmonary injury due to therapy-related causes.
Therefore, suppression of CYP2B1 and inducible CYP1A1 following CD and PAH exposure is associated with, but not caused by, up-regulation of Bax expression and apoptosis of alveolar cells.
Surfactant: Fluid secreted by alveolar cells that reduces the surface tension of pulmonary fluids and contributes to the elastic properties of pulmonary tissue.
The scatterers are alveolar cells in the barbs of the feathers.
In mink kits, AD causes an acute cytopathic infection of alveolar cells, which leads to respiratory distress and death (8).
However, it may also be underlain by a differential susceptibility of the airway epithelial cells when compared to the alveolar cells to this type of stimulation.
Further, the presence of CTGF protein in lung tissue of IPF patients appears to be confined predominantly to those cell types believed to play a critical role in pulmonary fibrosis (proliferating type II alveolar cells and activated fibroblasts).