Carvedilol targets both the beta- and alpha-adrenergic receptors
5) At that time, it was shown that aerobic exercisers had greater alpha-adrenergic receptor
density and significantly lower beta-adrenergic receptor density than weight trainers.
Multiple second messenger pathways of alpha-adrenergic receptor
subtypes expressed in eukaryotic cells.
Since then, scientists have discovered that the alpha-adrenergic receptor
family contains at least six subtypes (the alpha-1a, alpha-1b, alpha-1d, alpha-2a, alpha-2b and alpha-2c).
The number of beta-adrenergic receptors is reduced, usually with preservation of alpha-adrenergic receptors
and circulating catecholamines, causing beta/alpha-adrenergic imbalance, diastolic hypertension, reduced total blood volume, and other manifestations (3).