allele


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Related to allele: Dominant allele, multiple allele, Recessive allele
  • noun

Synonyms for allele

(genetics) either of a pair (or series) of alternative forms of a gene that can occupy the same locus on a particular chromosome and that control the same character

References in periodicals archive ?
Patients with one or two copies of the Asp40 allele and those who were homozygous for the Asn40 allele were randomized to naltrexone 50 mg a day or placebo and the primary outcome measured was relapse to heavy drinking during treatment.
The Allele Frequency Community database already holds more than 70,000 variant call datasets including 8,000 whole genomes and has been shown in internal benchmarking studies to generate a 43% average reduction in false positive rates in causal variant identification.
In marked contrast, samples carrying a PM or FM expanded allele (GM06891, GM06852, GM06907, and GM07537) showed clearly different melt profiles that dropped to baseline--dF/dT levels at or above 93[degrees]C.
The study showed that possessing one long allele increases the likelihood of being very satisfied with life by 8.
We examined allele frequencies for 12 polymorphisms in folate and MTX metabolism among healthy subjects and compared them with the allele distribution in other ethnic groups (Table I).
Of the 24 STs with only 1 informative allele, 18 were correctly assigned; only 4 were incorrectly assigned.
In East Asians, in whom the ADHIB*2 allele is found at high frequency, it is protective against alcoholism (Chen et al.
Noble believes, is that identification of the A1 allele early in a person's life could result in targeted and aggressive substance abuse prevention efforts for that person and others with the gene form.
Although previous studies had associated type 2 diabetes with the gene variations, in this study, researchers from Lund University in Malmo wanted to determine whether detecting common forms, or alleles, of nine diabetes-related genes could help single out those at a high risk.
Gordon explained that there is a spectrum of repeat triplet lengths for each allele, ranging from normal to expanded-normal--a pattern that might pose a "pool of instability for future generations"--to a long expanse of triplet repeat tracks, associated with the development of symptoms.
For this reason, and in light of our previous study, (2) the genotype that could influence coronary heart disease (CHD)--such as apolipoprotein E--was evaluated, and the patient was found to be homozygous for the [epsilon]4 allele.
Researchers can order primers to investigate the SNP of interest on both the sense and antisense strands as well as explore whether the template DNA is heterozygous or homozygous for a given allele.
An example would be HLA-B12, the original allele detected, being further split to HLA-B44 and -45.
2] allele also was associated with higher blood lead levels.