antibody

(redirected from agonistic antibody)
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GTC also obtained access from the Mayo Clinic to the commercial rights for an agonistic antibody to the CD137 receptor of the human immune system, also known as 4-1BB.
1- 13) Because HGS-ETR1 mimics the activity of the natural TRAIL-receptor 1 protein, it is considered an agonistic antibody.
GTC", Nasdaq: GTCB) has entered into agreements with Mayo Clinic to begin preclinical development of an agonistic antibody to CD137 as a potential therapeutic for solid tumors.
HGS-TR2J mimics the activity of native TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) and, thus, is considered an agonistic antibody.
Because HGS-ETR1 mimics the activity of native TRAIL when it binds to TRAIL Receptor 1, it is considered an agonistic antibody.