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A single group was given lisinopril by gavage at a dose of 10 mg/kg concomitantly with adenine
The methods used for simultaneous separation of Cr compounds and adenine
nucleotides generally include two types of protocols: (1) isocratic elution of these compounds in an organic solvent-free buffer followed by stepwise switch to another buffer contaning acetonitrile or methanol and (2) typical gradient elution method where Cr derivatives are eluted in isocratic conditions and adenine
nucleotides by organic solvent gradient elution.
To measure the secretory response of the platelets obtained from experimental subjects, the platelets were activated with 2[micro]M collagen and the level of secretion was measured in terms of release of serotonin, adenine
nucleotides, PPi, and Pi (Figure 1).
Adenosine, uridine, and thymidine produced ions that corresponded to the ion pairs of adenine
, uracil, and thymine, respectively.
Nucleic acids such as genomic DNA are composed of long strings of the bases Adenine
, Cytosine, Guanine and Thymine (A, C, G and T) held together by a backbone in a double strand formation in which Adenine
is always paired with Thymine and Cytosine with Guanine.
The measurement is based on the fact that the enzymatic reduction of diacetyl requires the cofactor nicotinamide adenine
dinucleotide phosphate (NADPH).
Creatine kinase (CK) is a 86 kDa homodimer that catalyzes the reversible synthesis of adenine
triphosphate (ATP) from the hydrolysis of phosphocreatine to creatine.
Mitochondria contain their own DNA and carry out oxidative phosphorylation, which produces most of the adenine
triphosphate in eukaryotic cells.
Two of five randomized, controlled trials involving immunologic therapy showed an overall beneficial effect, as did one randomized, controlled trial using drug therapy (oral reduced nicotinamide adenine
Team member Yuichi Ando said among the four nitrogenous bases -- thymine (T), adenine
(A), guanine and cytosine -- the researchers examined patient sequences of consecutive T and A bases called ''TATA boxes,'' which exist in genes activating enzymes that can prevent side effects of the drug.
Take a recent example of a firm that is getting the word out that a supplement called NADH (nicotinamide adenine
dinucleotide), an antioxidant form of vitamin [B.
He then translates the Morse code into the ACGTs of the genetic code, assigning word spaces to adenine
, dots to cytosine, letter spaces to guanine, and dashes to thymine.
Scientists do not know how many genes are contained within this vast string of As, Cs, Gs, and Ts-the 4 letters of the DNA alphabet representing adenine
, cytosine, guanine, and thymine.
binding is very small and is limited to the residues involved in binding of the adenine