We next examined P gingivalis LPS-induced acinar cell
Notably, acinar cells
have been shown to metabolize alcohol (i.
The acinar cell
adenomas we observed in the rats were characterized by being a discrete mass consisting of tubular and acinar structures composed of small acinar cells
with brightly eosinophilic cytoplasm and lacking zymogen granules.
carcinoma is a rare malignant exocrine pancreatic neoplasm, which accounts for less than 2% of pancreatic malignancy.
This is attributed to the larger amount of aqueous protein within the glandular elements, an abundance of endoplasmatic reticulum of the protein-producing acinar cells
, and the high content of paramagnetic ions, such as manganese, within the pancreas.
carcinoma of the pancreas with and without endocrine differentiation.
Two other pancreatic neoplasms that can be included in the differential diagnosis are the uncommon pancreatoblastoma and acinar cell
These are acinar cell
carcinomas, (56,57) pancreatoblastomas, (58) and solid-pseudopapillary neoplasms, (59,60) which frequently share the clinical scenario with PENs because of the presence of a slow-growing, pushing mass.
However, this PSA reactivity has also been described in acinar cell
carcinoma of the pancreas .
65) The pancreatic epithelium contains all the precursor cells of the mature organ and differentiates along islet cell, acinar cell
, and ductal cell lineages giving rise to the mature organ.
Sensitivities for specific diagnostic entities were as follows: 79% for ductal adenocarcinoma, 100% for acinar cell
carcinoma, 75% for pancreatic endocrine tumor, 70% for intraductal papillary mucinous neoplasms (IPMN), and 42% for mucinous cystic neoplasms (MCN).
Most pancreatic neoplasms are of exocrine type, which includes invasive ductal adenocarcinoma, intraductal neoplasms, pancreatic intraepithelial neoplasms, serous neoplasms, mucinous cystic neoplasms, and acinar cell
Cystadenoma (Cystic Acinar Transformation).
Many of the major types of pancreatic neoplasms (ductal adenocarcinoma, pancreatic endocrine neoplasm, acinar cell
carcinoma, pancreatoblastoma) typically form solid masses (Figure 4, A and B).
cytoplasm is usually finely granular, light green to gray on Papanicolaou stains and pink to light magenta on air-dried preparations.