Refining the level for anticipated hepatotoxicity in acetaminophen poisoning
saturates the glucuronide and sulfate stores, resulting in abnormally high NAPQI production (2) (Fig.
Treatment of severe acetaminophen poisoning
with intravenous acetylcysteine.
About 100 people die annually of accidental acetaminophen poisoning
, and another 15,000 are seen in hospital emergency rooms as a result of unknowingly taking too much.
Kawamura, a former painter who was hospitalized May 30 last year for liver disease apparently caused by acetaminophen poisoning
, had a life insurance policy worth about 1.
The FDA reports that at least 33 American children below age 13 have died of acetaminophen poisoning
from 1970 to 1991; 152 others suffered serious consequences that required hospitalization and, sometimes, produced permanent disability.
Researchers have demonstrated the ability of HepaLife's PICM-19 cells to mimic the human liver cell's natural response to acetaminophen poisoning
, a response enhanced through exposure to alcohol in recent experiments.
Acetylcysteine is the commonly recognized antidote for acetaminophen poisoning
The poorer prognosis associated with hepatic involvement in iron poisoning compared with acetaminophen poisoning
may be due to different histologic patterns of injury.
Kawamura, a former painter who was hospitalized May 30, 1999, for liver disease apparently caused by acetaminophen poisoning
, had a life-insurance policy worth about 1.
There are few treatment options available for acetaminophen poisoning