The abuse liability
of drugs such as benzodiazepines is influenced to a large extent by their interoceptive effects which can be modelled in laboratory animals using drug discrimination procedures.
If you decide to prescribe a hypnotic with abuse liability
, the newer alpha-1-selective benzodiazepine receptor agonists are preferable--as they would be for nonaddicted patients--because they are less likely to disrupt sleep architecture.
vii) After reviewing the available data concerning the pharmacological profile and dependence potential of zopiclone (4-methyl-l-piperazinecarboxylic acid ester with 6-(5-chloro-2-pyridyl)-6,7-dihydro-7-hydroxy-5H-pyrrolo-[3,4-b]pyrazin-5-one), the Committee asserted that zopiclone has low abuse liability
, and its therapeutic usefulness is considerable.
Differences in basal or EtOH-induced activation of the opioid system are thought to contribute to abuse liability
Sexual abuse liability
will protect you from allegations of sexual abuse due to negligence in your hiring, training, or supervisory practices.
As it emerged they use a Channel Islands-based insurance company to handle, among other things, sex abuse liability
Paul as a result of the sexual abuse liability
to the plaintiffs.
DeNoble says he answered, "It's the exact procedure that NIDA would use to demonstrate abuse liability
Dominant tech platforms like YouTube are able to abuse liability
protections as royalty havens, dictating terms so they can grab the value from music for themselves, at the expense of artists.
In addition, the settlement also resolves allegations that between February 2007 and September 2010 the company's sales representatives allegedly made false and misleading statements regarding the efficacy and abuse liability
of its other ADHD medicine Vyvanse to state Midicaid formulary committees and doctors.
On 26 June, Cambridge Cognition Holdings PLC declared that it is positive of meeting full-year expectations, following it succeeded deals with various pharmaceutical firms for eight human abuse liability
studies, worth approx.
Luke's Hospital, San Francisco, said, "The net result will be increased prescribing of other [schedule II] drugs, which may have greater abuse liability
and actually fuel rather than reduce an epidemic in progress.
These findings indicate that the ability of alcohol to stimulate dopamine release may play an important and complex role in its rewarding effects and abuse liability
In a study designed to address possible abuse liability
associated with p.
In an abuse liability
study, (6) 12 adults with histories of stimulant abuse received intravenous immediate-release (IR) d-amphetamine, 10 or 20 mg.