Studies on human primary immune responses to dengue infection have identified critical attachment sites on the virion
for neutralizing antibodies (4).
penetrates the cell then makes use of the metabolic machinery and pathways of the living cell to make copies of its nucleic acid and synthesisze protein subunit.
5), topographic imaging indicated that the surface of the virions
lose parts of envelope at low concentrations (3 x [TD.
Electron microscopy was claimed to show large amounts of "extracellular viral particles"; however, that could only have been demonstrated by isolating and purifying those particles and establishing that they were indeed virions
, and this had not been done.
This protein is a cellular cytidine deaminase that is encapsulated into assembling virions
in the absence of vif and is inhibitory during the next round of viral replication.
The p2 domain of HIV-1 Gag regulates sequential proteolytic processing and is required to produce fully infectious virions
Diagnosis of an adenovirus infection was made in these birds based on the presence of characteristic intranuclear viral inclusions and identification of paracrystalline arrays of appropriately sized virions
within these inclusions.
It was assumed that virions
were bound tightly to the fibrin matrix and could not be released in effective numbers (9).
To create a phage-display library, degenerate synthetic oligonucleotides are spliced inframe into one of the phage coat protein genes, so that the "guest" peptides encoded by the degenerate oligonucleotides are fused to the coat protein and thereby displayed on the exposed surface of the virions
[reviewed in Ref.
contain one molecule of linear double stranded DNA (van Regenmortel et al.
migrate to the host cell membrane where they may exit or wait until cell death.
This process results in many noninfectious virions
, a finding that is documented in virion
These particles contain Env anchored to the viral envelope, thus retaining native conformation, and although they neither replicate nor contain the HIV genome, they do closely resemble intact HIV virions
This sets the virions
loose inside the caterpillar, where they replicate and eat it "out of house and home," says Edward M.
Assembly and exit of virions
from cells at a glance.