recombinant

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Words related to recombinant

a cell or organism in which genetic recombination has occurred

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References in periodicals archive ?
On the other hand, the converse strategy of switching from denosumab to teriparatide resulted in a temporary decline in bone mineral density.
While in the past additional medications were recommended for osteoporosis, the current guidelines recommend against using raloxifene, ibandronate, teriparatide, menopausal estrogen therapy, or menopausal estrogen plus progesterone therapy for first-line pharmacologic treatment.
In our case we introduced teriparatide at the end of the surgical management.
We believe in continuing bisphosphonate therapy if the T score is subnormal at the time of prophylactic fixation, however, further studies are required to decide between stopping bisphophonates and starting treatment with Teriparatide.
Methods: We assessed 3 patient cohorts treated with teriparatide 20 pg once daily for up to 24 months: 1) PR Latinas, 2) US Latinas, and 3) white women on the US mainland (white women).
There is also a challenge we're faced with in clinical practice: that is, the lack of early hip BMD increase with teriparatide," added Dr.
Teriparatide is used in the management of osteoporosis, but only for specific indications-these include failed anti-resorptive therapy, severe fracturing disease, and glucocorticoid-induced osteoporosis with a markedly decreased BMD.
The model, using a full implementation of CRNs, was originally created to estimate the long-term clinical and cost-effectiveness of teriparatide use in high-risk osteoporosis patients in Sweden.
Teriparatide is a human recombinant parathyroid hormone (PTH 1-34) and is the only currently available anabolic agent used in the treatment of osteoporosis.
The Massachusetts General Hospital (MGH) investigators found that a treatment that combined denosumab (Prolia) and teriparatide (Forteo) was superior to single-agent treatment in a 12-month trial in women with postmenopausal osteoporosis.
The guidelines also advocate medical therapy with zoledronic acid or other bisphosphonate drugs--alendronate (Fosamax), risedronate (Actonel), or deno-sumab (Prolia)--or teriparatide (Forteo) for men with a history of hip or spinal fracture and men at high risk of fracture based on DXA results and clinical risk factors.
In the new study, a device with individual doses of the drug teriparatide sealed inside was implanted under the waistline in eight women with osteoporosis.