Extract Concentration Teratogenic Effect
(%) Head Tail Delayed malformation malformation Growth Control 0.
Therefore, the present study was designed to investigate the embryotoxic and teratogenic effects
of dimethoate on the early developmental stages of 'desi' chicks (G.
8) Some teratogenic effects
of VPA have been also been reported in animals.
It is concluded that the concentration (administered parentally) less than LD50 is devoid of teratogenic effects
in pregnant female mice and chicken embryos.
cardiovascular & teratogenic effect
of chronic intermittent noise stress.
9) Noda T et al (1 & 2) has reported the external malformations such as cleft mandible, left lower lip, Ankyloglossia etc and skeletal malformations such as fused ribs, cervical etc with the teratogenic effect
of di n butyltin diacetate and it is dose dependent.
According to the main principles of the teratology the evaluation of the teratogenic effect
of different harmful factors is performed considering mechanisms of effect, time of coincidence of teratogenic effect
with periods of intensive formation of the fetal organs and systems.
Dr Ito told BBC News: "Although the mechanism for the teratogenic effect
was made clear, the mechanism for its therapeutic effects remains unknown.
An apparent teratogenic effect
was associated with both ionic liquids, with only the offspring of treated mice exhibiting certain uncommon morphological defects, such as craniorachischisis, ectopia cordis, and ablepharia.
Immunopotentiation with rat splenocytes or GM-CSF was shown to partially normalize the teratogenic effect
of CP, and was also found to partially decrease the CP-induced apoptotic process and exhibited a tendency to normalize the expression of p53 and bcl-2 in embryonic head and liver (Savion et al.
Due to teratogenic effect
of retinoic acid, five out of thirty embryos belonging to the subgroup A1, and six embryos belonging to the experimental subgroup A2 did not survive.
papaya, it is necessary to assess its teratogenic effect
in order to establish its potential as source of toxic compounds for drug discovery and development.
Although malformations were observed, no significant teratogenic effect
is evident for HA in Xenopus embryos.
DISCUSSION: Zidovudine exerts its teratogenic effect
by inhibiting cell proliferation and cell differentiation thus causing hindrance in growth and development.
of diphenylhydantoin and/or fluphenazine in mice.