marker

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Related to Surrogate marker: bioequivalence trial
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Synonyms for marker

some conspicuous object used to distinguish or mark something

a writing implement for making a mark

References in periodicals archive ?
The original study concluded that62% of EpiFix patients achieved the surrogate marker endpoint of greater than 40% wound area reduction at 4-weeksvs.
Although we found that a thoracic aneurysm was more common in patients who had a juxtarenal aneurysm, those numbers were not hard enough to confidently say that the juxtarenal component is always predictive of a surrogate marker of thoracic aneurysm development.
However, surrogate marker changes have been observed even in patients whose viral populations did not exhibit the "shift," indicating that residual antiviral activity (in spite of drug resistance) may play a role.
Novartis Pharmaceuticals Corporation, East Hanover, NJ reports that first-ever clinical evidence shows Certican (everolimus - RAD) has significant potential to reduce graft vasculopathy, a surrogate marker for chronic rejection in heart transplant recipients.
Looking for a breakthrough -- a treatment good enough to be, in effect, approved by acclamation -- means we would not have to wait to solve the problem of immune-based surrogate markers, which will probably take years (and may be essentially unsolvable, if an effective immune-based treatment must first be proven by clinical endpoints before a surrogate marker can be established).
MassTrace intends to use this IP to validate its new metaprobe paradigm, which links a surrogate marker and a therapeutic drug to achieve faster, smaller, and more successful clinical trials.
The test measures cardiac T2* which is a highly sensitive surrogate marker for cardiac iron.
In 2012, the International Society of Amyloidosis (ISA) established and validated NT-proBNP response as an indicator of organ response and as a surrogate marker of survival in AL amyloidosis in approximately 1200 patients.
Traish found this treatment also reduced fasting blood glucose and hemoglobin A1c, a surrogate marker of hyperglycemia, suggesting that testosterone treatment may improve insulin sensitivity and hyperglycemic control.
The indication for use of ProAmatine[R] in the treatment of symptomatic orthostatic hypotension is based primarily on a change in a surrogate marker of effectiveness, an increase in systolic blood pressure measured one minute after standing, a surrogate marker considered likely to correspond to a clinical benefit.
The objective of this pilot study was to evaluate the chemopreventive effect of metformin on rectal aberrant crypt foci (ACF), which are an endoscopic surrogate marker of colorectal cancer.
The new analysis used the number of cardioversions that patients received during follow-up as a surrogate marker for recurrent AF, and the number of times they presented with AF during follow-up medical examinations as a surrogate measure for their overall AF burden.
If the study does not have a clear-cut, well-known endpoint, then a surrogate marker can be used.
Low levels of WNV antibodies in nestlings could serve as a surrogate marker of exposure in adult raptor populations.
Birth weight is a gross surrogate marker for shifts in a host of metabolic processes.