Schlemm's canal


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Related to Schlemm's canal: glaucoma, Trabecular meshwork, Tubal tonsil
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  • noun

Synonyms for Schlemm's canal

a circular canal in the eye that drains aqueous humor from the anterior chamber of the eye into the anterior ciliary veins

References in periodicals archive ?
VESNEO is thought to increase aqueous humor outflow by acting on both the uveoscleral (non-conventional) pathway via latanoprost acid, and trabecular meshwork and Schlemm's canal (conventional pathway) via nitric oxide signaling.
By disrupting the angiopoietin/ TIE2 signalling pathway in a mouse model of glaucoma, the mice could not generate Schlemm's canal, had elevated intraocular pressure (IOP) and went on to develop classic features of glaucoma.
The FDA has granted 510k clearance for the canaloplasty microcatheter for catheterization and viscodilation of the Schlemm's canal to reduce intraocular pressure (IOP) in adult patients with POAG.
Glaucoma can occur when this canal is either blocked or from a birth defect, resulting in a small or absent Schlemm's canal.
They also have a direct action by binding to receptors present on endothelial cells in Schlemm's canal, causing relaxation of intracellular tight junctions that eases the resistance to outflow.