The data on the inhibitory action by RU 486
therefore strongly suggests that the proliferative effects of progesterone are mediated through its receptor17.
stimulation of PGF2a production in isolated endometrial cells in short term culture.
In many countries (including France, where RU 486
with prostaglandin is now used widely for early first-trimester abortions), the laws controlling the availability of abortion exempt medical practitioners and women undergoing abortion from criminal liability.
In 1988, when the French minister of health approved the general use of the drug, opponents assailed RU 486
as a "chemical weapon" against the unborn.
Fuentealba, "Efecto Antifoliculogenico de la Antiprogestina RU 486
en la Mujer," References en Gynecologie Obstetrique, 1:175, 1993.
a) RU 486
Alone Is Ineffective And Poses Significant Adverse Effects, Complications, And Potential Risks
Sixteen months later, on May 16, 1994, Secretary Shalala announced an agreement had been reached whereby the French manufacturer, Roussel-Uclaf, would relinquish without remuneration the US rights to RU 486
to the Population Council, a non-profit, nongovernmental, scientific research organization based in New York.
Pro-choice groups have brought heavy pressure on President Bill Clinton to take steps to allow the importation and sale of RU 486
, extolling it as a preferred means of abortion.
I was pleased to read The Nation's May 13 editorial on RU 486
by Lawrence Lader, "Breaking the Ban.
Gore said he has instructed Waxman that "making RU 486
readily and widely available must be at the top of his priority list.
The clinical trials of RU 486
also involve a two-step process, with misoprostol as the second step.
patent rights to the abortion pill known as RU 486
The perfect solution for you," she tells me, "would be RU 486
, but of course it's not available in this country.
The French drug RU 486
(mifepristone) is a synthetic steroid that blocks the action of progesterone on the endometrium.
scientists from conducting research into non-abortion uses of RU 486
that could make it a boon to millions of Americans.