VIROPHARMA is the leader in RNA virus
antiviral technology, and we are pleased to be able to extend our own pharmaceutical research programs by applying our chiral template libraries to such important infectious disease problems," said Dr.
Under normal conditions, an RNA virus
latches onto a host cell and injects into that cell its RNA, which both replicates itself and directs the creation of new viral coats.
It is this unique process that ViroPharma will exploit for the development of specific and effective RNA virus
Hepatitis E virus (HEV), a causative agent of human hepatitis E, is a single-stranded positive-sense RNA virus
recently classified as the sole member of the genus Hepevirus in the family Hepeviridae (1,2).
The positive-sense polyadenylated single-stranded RNA virus
family Caliciviridae contains four genera, Norovirus, Sapovirus, Lagovirus, and Vesivirus (1).
Influenza A virus is an enveloped negative-strand RNA virus
, with eight genome segments that code for 10 proteins.
Initially, the disease was referred to as "mystery swine disease" until its cause was determined to be a positive-stranded RNA virus
, designated porcine reproductive and respiratory syndrome virus (PRRSV), that together with murine lactate dehydrogenase-elevating virus (LDV), equine arteritis virus, and simian hemorrhagic fever virus, belongs to the family Arteriviridae (6).
Influenza, commonly known as the flu, is an infectious disease that infects birds and mammals (primarily of the upper airways and lungs in mammals) and is caused by an RNA virus