RNA polymerase


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Related to RNA polymerase: RNA polymerase II
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  • noun

Synonyms for RNA polymerase

the enzyme that copies DNA into RNA

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clade time of ([dagger]) divergence ([double dagger]) PB2 KF609508 Minor Jul 2010 PB1 KF609509 Major Jun 2002 PA KF609510 Minor Mar 2012 HA KF609511 ND Oct 2005 NP KF609512 Major Jan 2001 NA KF609513 ND Sep 2010 M KF609514 Minor May 2011 NS KF609515 ND Oct 1996 * PB, polymerase basic subunit; PA, RNA polymerase acidic subunit; HA, hemagglutinin; NP, nucleoprotein; NA, neuraminidase; M, matrix gene; NS, nonstructural gene.
Transcription by single molecules of RNA polymerase observed by light microscopy.
f) The reaction mixture also contains a second enzyme--an RNA polymerase (in this case, T7 RNA polymerase).
We have repurposed a group of natural proteins, called integrases, to realize digital control over the flow of RNA polymerase along DNA, which in turn allowed us to engineer amplifying genetic logic," said Endy.
Kornberg and his colleagues at Stanford University School of Medicine suggests that other proteins link with RNA polymerase and form a different sort of holoenzyme that then starts transcribing DNA.
BCX5191 showed no inhibition of human RNA polymerase and no evidence of toxicity from standard in vitro screens.
Inhibitex is developing a series of proprietary nucleotide inhibitors that target the RNA-dependent RNA polymerase (NS5b) of HCV.
These experiments will shed light on the mechanochemical cycle of RNA polymerase, on its motion along a complex track, on the physical interactions that occur between helicases and proteins at termination, and on replisome dynamics near stall.
helminthoeca RNA polymerase [beta]-subunit (rpoB) (NH-rpoB-F: 5'-TGTCTTCGAAGGCCCAAAGACAGA-3" and NH-rpoB-R: 5'-AGAACCGATAGAGCGGGCATGAAT-3') (3) and heat-shock protein groESL (NH-groESL-F: 5'-AGGCTACTTCGCAGGCAAATGAGA-3' and NH-groESL-R: 5'-CACGCTTCATTCCGCCCTTTAACT-3') (4,5).
Andres Tellez, principal, business development and strategy, served as the lead author on a research article published in The Journal of Molecular Biology, entitled "Interstitial contacts in an RNA-dependent RNA polymerase lattice.
These were unique triple reassortant genotype viruses, with hemagglutinin (HA), neuraminidase (NA), and RNA polymerase (PB1) genes of human influenza virus lineage; nucleoprotein (NP), matrix (M), and nonstructural (NS) genes of classical swine virus lineage; and RNA polymerase (PA and PB2) genes of North American avian virus lineage.
Amplification of fragments of the F1L gene, an apoptosis modulator, and the rpo18 gene, the small subunit of viral RNA polymerase (1) (both genes are encoded by all poxviruses including variola virus), was monitored by gene-specific 5'-nuclease probes.
The virus genome consists of 3 segments of negative-stranded RNA; the large (L) segment encodes viral RNA-dependent RNA polymerase, the medium (M) segment encodes glycoprotein precursor, and the small (S) segment encodes nucleocapsid protein.
Abstract P-262: The Mechanism of Action of Beta-D-2'-Deoxy-2'-fluoro- 2'-C-methylcytidine Involves a Second Metabolic Pathway Leading to Beta-D-2'-Deoxy-2'-fluoro-2'-C-methyluridine 5'-Triphosphate, a Potent Inhibitor of the HCV RNA-Dependent RNA Polymerase.
High-level resistance to rifampin (MIC >32 mg/L) in Neisseria meningitidis is provoked by mutations (most frequently at the residue His 552) in the rpoB gene encoding the [beta] subunit of RNA polymerase (1,2).