1921) discovered relatively small molecules of RNA
in the cytoplasm.
Russell Burns, RNA
coordinator for the Forest Service, says, "The act tells us we have to monitor resource-management activity on national forests.
Original papers in RNA
Biology will represent a wide range of experimental systems, both prokaryotic and eukaryotic, and experimental approaches, including molecular and cell biology, biochemistry, genetics, genomics, and molecular medicine.
The structure of RNA
polymerase intrigued Kornberg because this enzyme begins the protein-making process.
Only 3 samples, all from seropositive children (ages 6, 7, and 13 years), had positive results by RT-PCR, and viral RNA
levels in these samples were 2.
The nematode Caenorhabditis elegans is the first organism in which dsRNA was used to silence RNA
(Fire et al, 1998).
In this study, we investigated the nature of circulating RNA
and tested possible mechanisms for its protection against plasma RNase activity.
Our key objectives are to present a comprehensive discussion of the current state-of-the-art in RNA
interference technologies, and to assess the present and future commercial potential for the key market segments.
On a macrostructural level, a more significant difference between DNA and RNA
is that RNA
is generally a single-stranded macromolecule, while DNA is double-stranded.
The ligation step of small RNA
library prep is ordinarily a source of severe bias.
The emergence of such enzymes in a primordial RNA
world -- which the new study shows was plausible -- could have overcome a key obstacle to the origin of life.
The quality of purified RNA
from tissues and cells is variable.
But a study of RNA
in white blood cells from 27 different people shows that, on average, each person has nearly 4,000 genes in which the RNA
copies contain misspellings not found in DNA.
The term "RNA
World" refers to a hypothetical time in the evolution of life on earth in which catalytic RNA
was the sole genetic material and in which the standard Watson-Crick pairing was the basis of genetic manipulation; a hypothesis that has been given a new lease on life due to the recent discovery of present-day RNA
molecules that do indeed display catalytic activity.
Depending on when you last formally studied biology and genetics, you may still think of RNA
as a simple messenger that is the intermediary between a gene's deoxyribonucleic acid (DNA) instructions and its protein end product.