Over 80 percent of RMSF
cases required emergency room visits, 14 percent were admitted to the intensive care unit for severe illness, and 7 percent were fatal.
Patients with RMSF
can be treated with rickettsial static agents chloramphenicol, tetracycline, or doxycycline.
is a race against time, and doctors must prescribe the drug early, before they have lab results confirming infection.
This statement is corroborated by a study that reported that 69% of the RMSF
cases in the Sao Paulo metropolitan area occurred in children and women, who usually did not enter the forest (habitat of A.
rickettsii; the dogs were therefore immune to RMSF
For clinical and surveillance purposes, it is essential to recognize that at least 3 tick genera, Dermacentor, Rhipicephalus, and Amblyomma, may be capable of transmitting RMSF
in the eastern and south-central United States.
According to Kohls (2), RMSF
transmission studies performed with supposed A.
parkeri has been recognized as a human pathogen only since 2004, when it was isolated from an eschar on a serviceman from Virginia (2), although an Ohio patient suspected to have RMSF
died of R.
serologic titers for a man who returned from Honduras, 2005 * Titers on specific date Test May 26 Jun 10 RMSF
IgG ([dagger]) Positive, [greater than or equal to] 1,024 RMSF
IgM ([dagger]) Positive, 512 R.
has been reported in North, Central, and South America, where different tick species serve as vectors (1).
At present, we know that MSF is at least as severe as RMSF
and has a mortality rate as high as 32.
Pulmonary involvement has been described in RMSF
, in which the pathology changes are thought to be related to noncardiogenic pulmonary edema consequent to capillary endothelial damage (10,11).
Although wearing long-sleeved clothing and using insect repellants can prevent tick bites, parents and physicians should still be alert to the possibility of RMSF
when a child experiences symptoms of fever, headache, and rash, whether or not a recent tick bite was recognized.
The case-fatality rate of untreated RMSF
in different areas is 10%-80%.
No reports of this disease (known locally as Fiebre de Yobia) have been produced from Colombia since, and currently RMSF
is generally not included in the differential diagnoses of febrile syndromes.