Mati's proprietary punctal plug
design has demonstrated excellent lower punctum retention rates of 92% and 96% over a 12-week follow-up period in two separate multi-center US clinical trials.
Mati's Evolute platform includes features for retaining the punctal plug
within the nasolacrimal system of the eye during drug elution and sustained release formulations currently in development for post-operative pain and inflammation.
The treatment of aqueous deficient dry eye with removable punctal plugs
Keywords: dry eye syndrome, symptoms, punctal plugs
, lasik, rose bengal
Until recently, there were just two treatments for dry eyes: over-the-counter artificial tear eye drops designed to replace your natural tears, or a non-surgical procedure called punctal plugs
in which tiny bits of silicon are inserted into the openings on the lower and upper lids where tears drain into the nose.
are a quick and easy method of occluding the drainage system (see Figure 2).
According to the company, the increased tear production was not seen in patients currently taking topical anti-inflammatory drugs or using punctal plugs
insertion was made simultaneously with bilateral lateral rectus recessions.
Ocular Solutions also distributes TLC Lid Hygiene Wipes and EagleVision punctal plugs
, dilators and gauges.
Current therapies: Allergan/Inspire Pharmaceuticals' Restasis, Eisai/Kissei Pharmaceutical's Salagen, Daiichi Sankyo's Evoxac, punctal plugs
, hydroxychloroquine, methotrexate, azathioprine
More severe cases can be managed with punctal plugs
(see Figure 3) and if this is not sufficient, surgical treatment to reduce ocular exposure can be effective.