prion

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  • noun

Words related to prion

(microbiology) an infectious protein particle similar to a virus but lacking nucleic acid

References in periodicals archive ?
They infected these cells in a Petri dish with prions isolated from brain samples of CJD patients.
Prion Biology: A Subject Collection From Cold Spring Harbor Perspectives in Biology
To ascertain the host range of different strains from cervids, we inoculated CWD prions isolated from experimentally infected deer with different PRNP genotypes (Q95G96 [wild type (wt)], S96/wt, H95/wt, and H95/S96) and from elk (CWD2 strain) into hamsters and mice.
and colleagues tested plant proteins for prion power by swapping bits of them into yeast prions.
This study represents an important first step for the tASA diagnostic protocol to gain regulatory approval for its use in TSE surveillance programs targeting CWD in cervids, commented noted authority Holger Wille, PhD, of the University of Alberta Department of Biochemistry and Centre for Prions and Protein Folding Diseases in Edmonton, Alberta (Canada).
It was eventually found that the men got the choicest cuts from vanquished human enemies leaving the women and children to consume the undesirable leftovers like brains where the largest density of infectious prions reside.
So far there has been no evidence for horizontal transmission of BSE in cattle, and prions have not been found in the milk, semen, or embryos of infected cattle.
As prions cause no inflammatory or immune response, there are currently no tests available to detect prion disease.
Washington, April 4 ( ANI ): American researchers have for the first time identified a pair of drugs already approved for human use that effectively acts against prion disease.
The team exposed controlled amounts of prions to various doses of ozone-saturated solution at a variety of temperatures and pH levels.
Summary: TEHRAN (FNA)- A joint study by scientists at Vanderbilt University and the University of California, San Francisco revealed the first direct information on the molecular structure of prions.
Topics addressed include the cell biology of prions, techniques and approaches for studying prion infections in cultured cells, how these systems can be used as a rapid bioassay, and prion protein misfolding.
Amyloidogenic domains, prions and structural inheritance: rudiments of early life or recent acquisition?
Prions infect and propagate by refolding abnormally and are resistant to destruction by heat, radiation, and other treatments.
A team of researchers from Japan and the United States claims it has bred cows that cannot contract mad cow disease because they do not have prions, a type of protein.