Benjamin Chan, a co-author of the study and associate research scientist in the Department of Ecology and Evolutionary Biology at Yale University, and his team of scientists, collected the phages
used in the treatment.
should be tested in animal models of skin infections to document their therapeutic potential.
Although it's too early to say if phages
can one day make a breakthrough in medical technology, tiny discoveries such as Putonti's study make just that idea within reality's reach.
Their sensitivity against three phages
indicated broad host range of phages
SANF and SA2, and relatively narrow host range of phage
Our research team set out to determine whether phages
can be effective at killing a large group of bacteria that have become resistant to antibiotics and cause deadly diseases in people," said corresponding author Dr.
are a common and important component of gut flora and are found in various other parts of the human body such as the mouth and skin.
In an attempt to understand mechanism of immune response elicited by phage
lysate in present study we are reporting the TLR mediated immune response of plain and alum adjuvanated phage
lysate of B.
are essential for life on earth and kill roughly half of all bacteria on the planet every two days.
The key characteristics of the biopreparations based on phages
are the following: the specificity of action, the quickness and validity of detection and the simplicity of performance.
Stephen Ahem, Mayukh Das (above), Tushar Suvra Bhowmick and Ry Young worked with Gonzalez to isolate phages
and determine their genetic diversity.
against Enterococcus faecalis, a life-threatening pathogen common in post-root canal infections, was isolated by the researches from sewage effluents gathered at a Jerusalem sewage treatment facility.
One avenue available involves the use of bacteriophages, also known as phages
Microbiologists, immunologists, and other biomedical specialists present virulent phages
as antibacterial agents and survey their main therapeutic applications.
are now used in many applications of biotechnology and in medical fields as alternatives to antibiotics, vector for protein, and DNA vaccines or as gene therapy delivery vehicles.
released from the dead bacterium can then infect other host cells," Clokie said.