As based on clinical studies of arteritic and nonarteritic anterior ION, optic disc swelling regresses over an 8- to 12-week period, leaving a pale optic nerve
(eg, optic atrophy).
The optic nerve
and internal carotid artery form two critical landmarks in the sphenoid sinus.
Magnetic Resonance Imaging (MR) (Figure 1, B) revealed mild left proptosis with diffuse inflammatory enhancement of the intraconal fat and optic nerve
sheath spanning mid orbit to apex.
In response to this situation, pediatric neuroophthalmologist Mark Borchert, director of both the Eye Birth Defects and Eye Technology Institutes in the Vision Center at Children's Hospital Los Angeles, realized that a controlled trial of sufficient size was needed to evaluate whether stem cell therapy is effective at improving optic nerve
function in children with ONH.
It develops from bilateral involvement of the uncrossed fibers at the chiasma such as bilateral internal carotid artery atherosclerosis or aneurysm, olfactory groove meningioma, empty sella syndrome, chronic raised intracranial pressure, and neurosyphilis affecting both optic nerves
Several had MRI scans, spinal taps, and computerized analysis of their optic nerve
He also revealed how his daughter is suffering from hypotonia and optic nerve
hypoplasia, or ONH.
In the Vaphiades (7) case, the optic nerves
continued to exhibit enhancement on a follow-up MR performed 16 weeks after surgery.
The unreactive pupils localise the pathology to the anterior visual pathway, which was confirmed by the finding of high signal in the posterior optic nerves
Optic neuritis involves inflammation or loss of myelin insulation of the optic nerves
The scientists then tested their new protein in live rats whose optic nerves
had been crushed.
Unfortunately, by the time symptoms begin to surface, permanent damage to the optic nerve
and vision loss have already taken root, highlighting the critical importance of early detection and treatment.
Patients with a family history of glaucoma need to insist that their ophthalmologists check their optic nerves
frequently to detect any signs of damage, or they may later find that they have suffered some irreversible optic nerve
loss while their intraocular pressure remained within normal limits.
1) Buus et al reported the case of a patient whose optic nerves
on both sides were severed during an intranasal ethmoidectomy.
Opticians found a clot behind one eye had stopped the blood supply to the optic nerves