Recombinant human Nerve Growth Factor
(rhNGF), developed and manufactured by the Dompe Group and based on the research ofNobel Prize winner Rita Levi Montalcini, recently received orphan drug designation from the European Medicines Agency (EMA) and the United States FDA regulatory agencies for the treatment of Retinitis pigmentosa.
In this review, we describe the most recent advances in the functions of brain derived nerve growth factor
(BDNF), a major type of neurotrophins, focusing primarily on cardiovascular and metabolic diseases.
And because Amgen has been developing its own nerve growth factors
, Engelberg said, the Guilford deal may signal that Amgen is uncertain about the prospects of its in-house products.
This discovery has prompted major interest in nerve growth factors
and how they might be employed in treating Alzheimer's.
In one experiment, geneticists determined that a particular docking site for nerve growth factors
plays a role in the success of some nerve cell connections.
Geron Corporation (Nasdaq: GERN) today reported that studies show GRNOPC1, the company's human embryonic stem cell (hESC)-based oligodendroglial progenitor therapeutic, produces multiple nerve growth factors
, proteins that stimulate the survival and regeneration of neurons damaged during spinal cord injury.