Drugs for Neglected Diseases
(DNDi), a non-profit research and development organisation developing new treatments for neglected diseases
and supported by Medecins Sans Frontieres, has calculated that, of the 1,556 new drugs approved between 1975 and 2004, only 21 (1.
BOSTON -- The annual number of new drug approvals worldwide to treat neglected diseases
has nearly doubled in recent years, with HIV/AIDS and malaria medications accounting for 60% of the most recent approvals, according to a newly completed analysis from the Tufts Center for the Study of Drug Development (CSDD).
Elimination of neglected diseases
in Latin America and the Caribbean: a mapping of selected diseases.
Initiatives such as Genzyme's Humanitarian Assistance for Neglected Diseases
and Alnylam's Intellectual Property (IP) contributions to the Pool for Open Innovation against Neglected Tropical Diseases show a commitment to helping produce badly needed health technologies, but unmet needs for new drugs, vaccines and diagnostics for diseases affecting developing countries remain.
For example, FDA can now award a priority review voucher (PRV) to any company obtaining approval for a product that prevents or treats a neglected disease
A company that receives approval for a new neglected disease
treatment in the U.
The NIH can now assist in this high-risk area through the Therapeutics for Rare and Neglected Diseases
(TRND) program in its Office of Rare Diseases Research.
Collins said he was particularly excited about five instances in which the NIH is using this new model of helping to "de-risk" the drug development process for orphan or neglected diseases
Although hypertension is relatively easy to prevent, simple to diagnose and relatively inexpensive to treat, it remains the second leading cause of death among Americans, and as such should rightly be called a neglected disease
," said David Fleming, MD, the report's authoring commit tee chair as well as director and health officer of public health in Seattle and King County.
Against this backdrop, the authors suggest creating a scheme that offers new incentives for research on diseases disproportionately affecting the poor, with the goal of making development of neglected disease
vaccines a lucrative endeavor for pharmaceutical companies.
A more well-known neglected disease
in industrialized countries, because it affects travelers to, as well as residents in, tropical countries, is malaria.
The report shows that 134 biotechnology companies are participating in neglected disease
research and development, which represents participation in 39% of the 191 new drugs, vaccines, and diagnostics in development for neglected diseases
such as malaria, tuberculosis, dengue fever, and others.
Peshawar -- The neglected disease
cutaneous leishmaniasis is on the increase in Pakistan's Federally Administered Tribal Areas (FATA), according to reports by FATA's Directorate of Health.
It will grant all commercial and intellectual property rights in neglected disease
areas to non-profit partners.
During the press briefing, which is being held at 9:00am ET on June 18, a report developed by BVGH and BIO titled Biotechnology: Bringing Innovation to Neglected Disease
Research and Development will be publicly released.