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Related to Molecular chaperone: Chaperone molecule
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Synonyms for chaperone

one who accompanies and supervises a young woman or gatherings of young people

accompany as a chaperone


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References in periodicals archive ?
Small heat-shock proteins (sHSPs) represent an abundant and ubiquitous family of molecular chaperones.
Molecular chaperones, like their human counterparts, prevent inappropriate liaisons between their charges and tempters that would lead them astray.
Hsp90 is a molecular chaperone required for the proper folding and activation of many cancer-promoting proteins, and is recognized as a key facilitator of cancer cell growth and survival.
Washington, June 21 (ANI): Scientists have shown a molecular chaperone is working like a waste management company to collect and detoxify high levels of toxic amyloid beta peptide found in Alzheimer's disease.
Opportunity to develop molecular chaperone therapy for the treatment of lysosomal storage diseases -
Heat Shock Protein 90 (Hsp90) is a molecular chaperone that mediates the post-translational stability of its protein substrates, many of which are validated oncogenes.
In addition, CytRx is developing two drug candidates based on its industry-leading molecular chaperone technology, which aims to repair or degrade misfolded proteins associated with disease.
To our knowledge, this is the first demonstration that inactivation of a specific molecular chaperone from the mouse prostate epithelial cells can potently block prostate cancer development and suppress the activation of AKT, which is a protein kinase that promotes cell proliferation and survival and is a major factor in many types of cancer," she said.
CytRx currently has two orally administered, clinical-stage molecular chaperone drug candidates and recently discovered a series of additional compounds that may provide a pipeline for additional drug candidates.
We are looking for opportunities to capitalize on the value of our molecular chaperone assets to further support our oncology focus.
We plan to take aggressive steps to further develop our promising molecular chaperone portfolio, including clinical-stage arimoclomol and iroxanadine, which target diabetic complications and neurodegenerative diseases and disorders.
Molecular Chaperone Regulator Candidates: In addition to its oncology franchise, CytRx is developing two drug candidates, arimoclomol and iroxanadine, based on its industry-leading molecular chaperone technology, which aims to repair or degrade misfolded proteins associated with disease.
Haen will discuss recent developments, including clinical program updates with its oncology and molecular chaperone drug candidates, during a company presentation at the Lippert/Heilshorn & Associates Life Sciences Virtual Conference.
LOS ANGELES -- CytRx Corporation (NASDAQ:CYTR), a biopharmaceutical company, is permitted to re-enter the clinic with its orally administered molecular chaperone drug candidate arimoclomol as a therapeutic treatment for amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease), following the U.
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