South San Francisco, California-based biotechnology company Genentech, a member of the Roche Group (SIX: RO) (OTCQX: RHHBY) has released encouraging results from the Phase II BOULEVARD study of RG7716 for the treatment of diabetic macular edema
(DME), the company said.
This trial is a randomized, double-blind, active-control, multi-center study in patients with diabetic macular edema
to compare the safety, efficacy and immunogenicity of M710 with EYLEA.
Methods: Seventy-two eyes of 59 patients with diabetic macular edema
were divided into two groups of 41 eyes (Group-A) and 31 eyes (Group-B).
Recalcitrant DME was defined as persistent macular edema
with CFT [greater than or equal to]300 [micro]m, lasting 3 months after at least 3 intravitreal anti-VEGF and 3 IVTA injections with 2 sessions of focal grid laser photocoagulation.
Comparison between optical coherence tomography and fundus fluorescein angiography for the detection of cystoid macular edema
in patients with uveitis,"Ophthalmology.
Treatment techniques and clinical guidelines for photocoagulation of diabetic macular edema
In diabetes, vision loss is most commonly the result of diabetic retinopathy (DR) and diabetic macular edema
(DME) (6), frequent diabetes complications present in as much as 34.
In a retrospective study, OCT scans of diabetic patients with macular edema
were reviewed and 24% of the cases were associated with vitreofoveal or extra foveal vitreous traction, out of which, 56% had vitreofoveal traction and 44% had extrafoveal traction8.
The report provides a snapshot of the global therapeutic landscape of Macular Edema
Incidence of clinical cystoids macular edema
is 2% in uncomplicated cataract surgery in our study.
In later stages, it is often complicated with macular edema
(ME) which may cause an additional visual reduction that often exceeds the previous ischemic damage, and thus macular edema
represents an important treatment target .
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Researchers said the study supports longer-term use of intravitreal bevacizumab for macular edema
The Food and Drug Administration has approved ranibizumab for treatment of diabetic macular edema
Retinal hemorrhages and macular edema
decreased clinically on examination on consecutive follow up visits.