86) Both agreements required Abbott to pay several million dollars in exchange for the generics forbearing from market entry until a specified date, until some other generics firm successfully brought a generic equivalent of Hytrin
to market, or until a final unappealable ruling holding the patents in question invalid.
Its main competitors are Hytrin
, or terazosin, and Pfizer Inc.
These were: Hytrin
, Abbocin, Clindacin, Vancomycin, Pedialyte and Pediasure Powder.
Medications recently approved for the treatment of BPH are Proscar (finasteride) and Hytrin
is the only alpha blocker now approved for BPH treatment by the Food and Drug Administration.
Nerve Blockers Generic Name Trade Name rauwolfia derivatives Reserpine guanethidine Ismelin guanadrel Hylorel alpha methyldopa Aldomlet clonidine Catapres guanabenz Wytensin prazosin Minipress terazosin Hytrin
Beta Blockers propranolol Inderal metoprolol Lopressor nadolol Corgard atenolol Tenormin timolol Blocadren pindolol Visken acebutolol Sectral labetolol Normodyne or Trandate Blood Vessel Dilators hydralazine, Apresoline minoxidil Loniten(**) Hormone inhibitors captopril Capoten enalapril Vasotec lisinopril Prinivel or Zestril Calcium Channel Blockers nifedipine Procardia verapamil Isoptin or Calan diltiazem Cardizem nicardipine Cardene
BPH, alpha blocker), carvedilol (e.
Abbott's patent was directed to crystalline forms of terazosin hydrochloride, which is the active ingredient in Hytrin
began the FDA approval process for its generic Hytrin
5 million per month to delay, the entry of its generic Hytrin
product, potentially costing consumers hundreds of millions of dollars a year.
The company has received approval for a generic version of Hytrin
Commonly used alpha blockers include Minipress, Hytrin
Proscar, one of the most commonly used drugs in the United States for BPH, is associated with gastrointestinal distress and impotency Hytrin
is used even less frequently for BPH because of side effects such as hypotension, edema, dizziness, nasal congestion, chest pain, and impotency, he noted.
Another drug, Hytrin
, produced by Abbott Laboratories, North Chicago, Ill.
For example, in the Hytrin
case, (130) Geneva Pharmaceuticals (a wholly-owned subsidiary of Novartis) filed two ANDAs.