Although the incidence of HIV-associated dementia
has decreased with HAART, the incidence of HIV-associated dementia
has actually increased from 6.
Retrograde amnesia in dementia: comparison of HIV-associated dementia
, Alzheimer's disease, and Huntington's disease.
Semantic clustering inefficiency in HIV-associated dementia
CSF soluble Fas correlates with the severity of HIV-associated dementia
In patients with longstanding HIV infection, brain imaging may reveal cerebral atrophy, which may accompany the cognitive changes found in HIV-associated dementia
Significantly increased levels of lactate and lipid biomarkers were noted in all HIV patients, those who tested normally on neuropsychological tests as well those with mild neurocognitive disorder and HIV-associated dementia
, compared with controls.
At the same time, NO is the main mediator of mitochondrial dysfunction associated with HIV central nervous system symptoms, with an increased production of NO related to HIV-associated dementia
Four significant diseases associated with HIV and AIDS are addressed: HIV-associated dementia
, peripheral neuropathy, cryptococcal meningitis, and toxoplasmosis.
The most severe form of NP impairment, HIV-associated dementia
, has become rarer since the arrival of triple antiretroviral combinations.
The links between HIV and mental health are multiple: risk taking associated with HIV acquisition is more common among individuals with mental disorders; common mental disorders (such as anxiety, depression and alcohol/ substance disorders) are often caused in part by the stress of an HIV diagnosis and related stigma; psychotic states are a relatively common presentation of HIV-infected individuals; and neurocognitive manifestations of HIV infection such as HIV-associated dementia
emerge later in the course of disease.
If this is the case in all of sub-Saharan Africa, HIV-associated dementia
may be one of the most common, but thus far unrecognised, dementias worldwide," Sacktor says.
Neurocognitive impairment is a common complication of HIV infection, presenting as a wide spectrum of disorders ranging from mild forms of HIV-associated minor cognitive--motor disorders to severe forms of cognitive impairment, termed HIV-associated dementia
While decreases are observed in deaths from CMV, wasting, and HIV-associated dementia
, increases are reported in deaths from sepsis, and diseases of the liver, kidney, and heart.
The most severe manifestation of CNS disease is HIV-associated dementia
complex (HADC), a neurological syndrome characterized by disordered mental functions (i.
1) HIV-associated dementia
(HAD) has also been referred to as HIV encephalopathy or AIDS dementia complex.