25],,,,, However, it was unclear why and how the immune response be triggered in chronic HBV patients; even though, they are in the condition of high levels of HBV DNA, HBeAg
, and HBsAg.
The main antigens and antibodies used for HBV evaluation were HBsAg, HBeAg
, anti-HBs, and anti-HBe.
Magnius and Espmark in 1972 discovered the HbeAg
and over years the exact functions still have to be completely understood3.
The presence of HBeAg
is a fairly reliable marker of HBV replication.
Hepatitis B virus is a partly double-stranded DNA virus with several serological markers: HBsAg and anti-HBs, HBeAg
and anti-HBe, and anti-HBcIgM and IgG (Trepo et al.
Though the exact numbers of women who were tested for Rubella IgM and HbeAg
are not known, but ATSJF members put it at 500.
In this, 10% were HBeAg
positive and 2% had HBV DNA > [10.
Respecto a perfil con posible infeccion, se hallaron ocho (1,3%) donantes con marcadores de infeccion cronica, uno (0,2%) presento una posible Hepatitis B con reactividad solamente para HBsAg, dos (0,3%) donantes no fueron clasificados en ningun estadio y sus muestras fueron doblemente reactivas para HBeAg
8 If the mother is HBsAg positive and is also positive for HBeAg
(a marker for infectivity) then there is a 90% chance that she will transmit the disease to her newborn.
Returning of ALT values to the normal ranges (<40 U/L) in the follow-up or at the end of treatment was considered biochemical response, elimination of HBeAg
and occurence of Anti-HBe was considered seroconversion, decrease of serum HBVDNA to an undetectable level and loss of HBeAg
and occurence of Anti-HBe in HBeAg
positive patients was considered virological response, presence of biochemical and virological response (seroconversion and loss of HBVDNA) together was considered full response and loss of biochemical response, virological response and HBsAg and occurence of antiHBs was considered full viral eradication.
7%) were found positive of which 27 (22%) showed HBeAg
Otros marcadores como el HBeAg
, titulos elevados del genoma viral (carga viral) y niveles altos de aminotransferasas (ALTs) pueden ser detectados.
For students who received the hepatitis B vaccine and the hepatitis B vaccine immune globulin as infants, 15 percent tested positive for a hepatitis B antigen known as HBeAg
Chronic hepatitis B can be subdivided into HbeAg
positive and HBeAg
-negative chronic hepatitis B (1,2).
Those with a response--a loss of the HBeAg
with HBV DNA less than 200 IU / mL at 48 weeks - received an additional 24 weeks of consolidation therapy with entecavir and then discontinued therapy.