CAZ-AVI (ceftazidime-avibactam) is an investigational antibiotic being developed to treat serious Gram-negative bacterial infections
A snapshot of the global therapeutic scenario for Gram-Negative Bacterial Infections
In general gram-negative bacterial infections
are increasing in intensive care units than gram-positive bacterial infections.
WASHINGTON -- Fluoroquinolone resistance rose significantly over an 8-year period in hospitalized adults aged 65 years and older with gram-negative bacterial infections
The drug is currently also being studied in a second complicated skin infection trial (STRAUSS II) targeting both Gram-positive and Gram-negative bacterial infections
, including patients with diabetic foot infections; and in phase III clinical trials in nosocomial pneumonia (CHOPIN studies) and in patients hospitalized with community-acquired pneumonia.
Gram-negative bacterial infections
in immunocompromised hosts in whom oral therapy is desired or resistance to alternative agents is present.
Discovered by Toyama Chemical, T-3811 is a new type of broad-spectrum quinolone antibiotic for treating Gram-positive and Gram-negative bacterial infections
However, endotoxemia in liver transplant recipients has been associated with graft failure and a high mortality rate (4,5), and in gram-negative bacterial infections
, the physiologic effects of endotoxin may persist after adequate antimicrobial drug treatment.
They resurrected the drug for use in a series of patients with Gram-negative bacterial infections
resistant to quinolones, broad-spectrum cephalosporins, carbapenems, and the other commercially available agents.
M2 EQUITYBITES-March 14, 2017-Pfizer Inc unveils novel combination antibiotic Zavicefta for the treatment of Gram-negative bacterial infections
in the UK and Germany
meningosepticum infections are rare, accurate diagnosis is important because the species is usually resistant to multiple antibiotics, especially to those (including extended-spectrum [Beta]-lactam agents and aminoglycosides) typically prescribed for treatment of aerobic, gram-negative bacterial infections
It also reviews key players involved in the therapeutic development for Gram-Negative Bacterial Infections
Pfizer's (NYSE:PFE) novel combination antibiotic for patients with serious Gram-negative bacterial infections
, Zavicefta, has been launched in the UK and Germany, the company announced on Tuesday.
M2 PHARMA-March 14, 2017-Pfizer Inc unveils novel combination antibiotic Zavicefta for the treatment of Gram-negative bacterial infections
in the UK and Germany
CXA-201 is currently being studied in pivotal Phase 3 trials as a first-line intravenous therapy for the treatment of complicated intra-abdominal infections and complicated urinary tract infections caused by Gram-negative bacterial infections
, including those caused by multi-drug resistant Pseudomonas aeruginosa.