Patients with confirmed Gram positive
skin infections will be included in the study and randomized to receive either active drug or placebo in cohorts at ascending dose levels.
, reagents for the identification and sensitivity.
Active against a broad range of gram positive
and negative bacteria, these agents are being developed as anti-infective medical device coatings (Ceracides(TM)) and as therapeutics for antibiotic-resistant organisms.
Some gram positive
bacteria not only invade tissue but release highly destructive toxins, such as the notorious "flesh eating" toxin of certain Streptococcus strains.
Ionic silver is well accepted as an antiseptic and is a proven broad-spectrum antimicrobial agent that eradicates gram positive
and gram negative bacteria including antibiotic-resistant bacteria like methicillin-resistant Staphylococus aureus (MRSA) and Vancomycin-resistant Enterococcus (VRE).
Food and Drug Administration has granted the Company clearance to market its Sensititre(R) Gram Positive
Identification Panel for use in conjunction with the Sensititre(R) Microbiology System for the automated identification of clinically significant Gram positive
bacteria, according to Peter P.
The free-flowing design of the patented Pathways(TM) Solid Drain Sanitizer does not obstruct water drainage, and it has been proven to be effective against a broad spectrum of gram negative and gram positive
organisms found on environmental surfaces, such as Staphylococcus aureus, Enterobacter aerogenes, Escherichia coli, Pseudomonas aeruginosa, Listeria monocytogenes, and Salmonella typhimurium.
A 510k filing to seek clearance on the gram positive
bacterial ID test is expected to be submitted to the FDA sometime in 1994.