The amount of thiocyanate in the urine is also a good indicator for the presence of goitrogen
in foods (25).
The thresholds for the hormonal changes may be different for different individuals because of variations in dietary iodide intake, exposure to other goitrogens
, age, and physiologic conditions.
Variable effects of goitrogens
in inducing precocious metamorphosis in sea lampreys (Petromyzon marinus).
Because PBDEs have the ability to interfere with thyroid hormone (TH) homeostasis, we included a reference group for TH-mediated effects by adding the goitrogen
6-n-propyl thiouracil (PTU) in the drinking water of pregnant females.
This suggests that there might be other goitrogens
or factors playing a role besides iodine deficiency that need to be explored.
9) Known goitrogens
include perchlorate (found in food and drinking water (10)), nitrate (also found in food and drinking water (11)), and thiocyanate (found in cigarette smoke and in cabbage, brussels sprouts, and other cruciferous vegetables (12)).
The seeds contain also bioactive proteins such as [alpha]-amylase, cytochrome, lectin, lipoxygenase, urease, TI, secondary metabolites including isoflavones, saponins, phytic acid, oligosaccharides and goitrogens
(Friedman and Brandon, 2001).
Compounds known as goitrogens
in soy, broccoli, and cauliflower can disturb thyroid functions in susceptible individuals with iodine deficiency.
Despite the correction of iodine deficiency in most areas, endemic goiter still persists in regional areas, indicating the additional pathogenetic role of genetic factors and/or naturally occurring goitrogens
The figure of 150 [micro]g/day in adults is based on the following assumptions and observations, and in order to provide an extra margin of safety and to meet increased demand that may be imposed by naturally-occurring goitrogens
under certain condition.
It has been thought that goitrogens
, natural chemicals in soy, interfere with iodine absorption in the thyroid.
Sonia, Donnybrook Dear Sonia, SOME foods contain natural goitrogens
,chemicals that cause the thyroid gland to enlarge.
AMEMBERS of the brassica family, such as cabbage, cauliflower, spinach, Brussel sprouts, broccoli and turnips, contain substances known as goitrogens
(goitre forming) that interfere with the action of iodine and may make symptoms of an underactive thyroid worse.
Chalmers also warns against chemicals called goitrogens
that could cause problems for those taking thyroid medication.
4]) levels, but no studies have reported individual measures of thyroid function and these goitrogens