A detailed study may be conducted in the area to find out the risk factors associated like autoimmune thyroiditis, goitrogens
, environmental Iodine content, etc.
Transient congenital hypothyroidism in an iodine-replete area is not related to parental consanguinity, mode of delivery, goitrogens
, iodine exposure, or thyrotropin receptor autoantibodies.
Effect of iodine intake on thyroid iodine distribution and thyroid weight of rats treated with thiouracil and other goitrogens
These observations suggest that there might be other goitrogens
or deficiency of other micronutrients responsible for the persistence of goitre despite adequate salt iodization.
9) Known goitrogens
include perchlorate (found in food and drinking water (10)), nitrate (also found in food and drinking water (11)), and thiocyanate (found in cigarette smoke and in cabbage, brussels sprouts, and other cruciferous vegetables (12)).
Other factors, such as goitrogens
or autoimmunity, may have a role in the still high prevalence of goitre in school children of Isfahan.
Compounds known as goitrogens
in soy, broccoli, and cauliflower can disturb thyroid functions in susceptible individuals with iodine deficiency.
Vegetables such as cabbage, soybeans, lentils, linseed, peas, peanuts, and all of the mustard-like plants possess goitrogens
Despite the correction of iodine deficiency in most areas, endemic goiter still persists in regional areas, indicating the additional pathogenetic role of genetic factors and/or naturally occurring goitrogens
The figure of 150 [micro]g/day in adults is based on the following assumptions and observations, and in order to provide an extra margin of safety and to meet increased demand that may be imposed by naturally-occurring goitrogens
under certain condition.
It has been thought that goitrogens
, natural chemicals in soy, interfere with iodine absorption in the thyroid.
Sonia, Donnybrook Dear Sonia, SOME foods contain natural goitrogens
,chemicals that cause the thyroid gland to enlarge.
These factors include trypsin inhibitors, hemagglutinins, saponins, isoflavones, and goitrogens
AMEMBERS of the brassica family, such as cabbage, cauliflower, spinach, Brussel sprouts, broccoli and turnips, contain substances known as goitrogens
(goitre forming) that interfere with the action of iodine and may make symptoms of an underactive thyroid worse.
Chalmers also warns against chemicals called goitrogens
that could cause problems for those taking thyroid medication.