that wrap insulation called myelin around axons (long projections from neurons) to speed up electrical signals
The new radial glial cells
act like those found in the developing fetal brain and direct the migration of newly generated neurons out into the deep tissues of the brain.
This report in Science is a major step in underscoring the importance of our work and focusing attention on glial cells
as the key to creating targeted therapies for chronic pain and other debilitating central nervous system disorders," commented Dr.
1 Neuron, scientists demonstrate that the protein neuregulin-1 type III (NRG1-III), which is produced by nerve cells, is essential to triggering glial cells
to make myelin.
Barres said the relationship remained hidden in past research because of the neuron's complete dependence on glial cells
for survival in a lab dish.
2002) with the astrocyte marker GFAP, we found that postnatal CPF treatment evoked an initial deficit, which is consistent with the view that CPF targets the replication and differentiation of these particular glial cells
(Barone et al.
The resulting abundance of the neurotransmitter appears to kill neurons and create room for the cancerous glial cells
to grow in the limited space within the skull.
It could also be extended to target distinctive neurons and glial cells
in the brain and spinal cord, and have far-reaching therapeutic effects.
Beta-amyloid, which is a protein fragment deposited in the brains of patients who have Alzheimer's disease, causes the activation of glial cells
In the developing brain, mercury kills nerve cells, destroys glial cells
that connect cells of the nervous system, and interferes with the organization of brain tissue.
The exciting thing is that there are more and more ways in which neurons and glial cells
are shown to interact," says Eric A.
These glial cells
form the myelin sheath that insulates nerve cells and is essential for their proper functioning.
The new work, conducted in the Waisman Center laboratory of UW-Madison neuroscientist Su-Chun Zhang, reveals the pervasive influence of Pax6 on the neuroectoderm, a structure that arises early in embryonic development and that churns out the two primary forms of brain cells - neurons and glial cells
- and the hundreds of cell subtypes that make up the human brain.
Cholinesterase plays a nonenzymatic role in the proliferation of glial cells
(48,49), and it is possible that physostigmine affects structural aspects of the cholinesterase molecule in a manner different from that of chlorpyrifos or chlorpyrilos oxon; further study will be needed to characterize any such effect.
Scientists in Spain disabled the hind limbs of nine rats by severing their spinal cords, then promptly injected olfactory glial cells
at each severed end.