9] A frequent observed and unwanted side effect of phenytoin, an anticonvulsant medication, is gingival hyperplasia
, especially in children.
(GH) or gingival overgrowth is a well known side effect of cyclosporine, calcium channel blockers such as nifedipine and anticonvulsants (3,4).
Table 1) with special reference to gingival hyperplasia
is considered to be a serious adverse effect due to its unaesthetic appearance and also due to its various complications like gingival bleeding, pain, teeth displacement and periodontal disease.
Clinical manifestations of CD include the presence of aphthous ulcerations, gingival hyperplasia
, diffuse gingival swelling, xerostomia, mucosal hyperplasia, cobblestoning of buccal mucosa, mucosal tags, fissuring cheilitis, OFG and orofacial CD.
Idiopathic gingival hyperplasia
and orthodontic treatment: a case report.
Interdisciplinary management of a patient with a drug-induced gingival hyperplasia
Key Words: Autosomal recessive disease, Gingival hyperplasia
, Nodular swellings, Chondroid cells, Juvenile hyaline fibromatosis
Hyalinization of various body tissues like skin, joints, and bones leads to development of skin papules, gingival hyperplasia
, osteolytic lesions in bones, and joint contractures.
Born in Mexico in 1834, Julia Pastrana suffered from hypertrichosis and gingival hyperplasia
, diseases that gave her copious facial hair and a thick-set jaw.
Relationship between gingival hyperplasia
and class II histocompatibility antigens in renal transplant recipients.
It has been estimated that 25-80% of patients on a regimen of CsA experience gingival hyperplasia
(Lawrence et al.
14,15) Although the presence of myofibroblasts has been reported in hereditary gingival fibromatosis (16) and drug-induced gingival hyperplasia
, (17,18) few studies have evaluated its presence in focal reactive overgrowths of the gingiva.
Nifedipine aggravates cyclosporine A-induced gingival hyperplasia
Excision and/or recontouring of gingival hyperplasia