gene

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Related to Gene transfer: gene therapy, vertical gene transfer
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References in periodicals archive ?
This pivotal trial, called FLOURISH (Heart Failure with Reduced Left Ventricular Ejection Fraction: One-time Gene Transfer Using RT-100 - Intracoronary Administration of Adenovirus 5 encoding Human AC6), is expected to commence in Q1 2018 in the US.
Elucidation of the mechanisms involved could lead to a better understanding of why some protozoa can promote gene transfer between bacteria.
This study showing a higher level of gene transfer in the reef environment than previously known has the potential to help scientists understand how DNA is being transferred and whether transfers help reefs adapt to environmental challenges.
Patient advocates have often misconstrued gene transfer trials as aimed at delivering therapy, and researchers have frequently contributed to this conflation of research and therapy.
The somatic gene transfer method allows dose-dependent detection of TH agonists in brain and muscle.
Until now, though, scientists did not know which of a bacterium's genes came from lateral gene transfer and which had been inherited from its parent.
Since then several other techniques for gene transfer such as sperm vector, electroporation, high-velocity microprojectile bombardment, and sperm electroporation, have been developed.
Although the researchers aren't sure how the gene transfer took place, they speculate that it required tight physical contact between the parasites and their host plants.
5) Since then, we have continued to warn our regulators that the CaMV 35S promoter will be extra prone to spread by horizontal gene transfer and recombination (6-8).
Jeffrey Isner, who in 1994 conducted the world's first clinical trials on gene transfer to treat patients with severe peripheral vascular disease.
In spite of many preclinical studies demonstrating the efficacy of vascular gene transfer strategies to prevent neointimal formation following arterial injury, the long-term clinical success of such strategies is dependent on the demonstration of safe and effective delivery of vectors into diseased target vessels.
Of the 5 mice in the study, all showed improvement within 15 weeks of gene transfer, and while the anemia was not completely cured, symptoms were reduced.
Anderson recalls, "because they demonstrated two vital components of gene therapy: first, that a functional human gene could be successfully inserted into the blood cells of a monkey, and second, that gene transfer using retroviruses was not harmful.
Immunology after in utero and neonatal gene transfer (Simon Waddington).
Experience in human gene transfer trials showed that targeting hepatocytes with V vectors has the potential to correct diseases like hemophilia, congenital blindness, and lipoprotein lipase deficiency.