Slow gastric distention
activated the posterior insula, the left posterior amygdala, and the sensorimotor cortices.
Purging may lead to excess alkalinity of the blood, potassium deficiency leading to atrial and ventricular arrhythmias and sudden cardiac death, aggravated hypotension with orthostatic blood pressure changes, gastric distention
and even rupture, esophagitis and esophageal tears, loss of dental enamel and tooth breakage, aspiration of gastric contents leading to aspiration pneumonia and choking death, and chronic exposure of the esophagus to gastric acid leading to Barrett's esophagus and possible esophageal cancer.
Transient LES relaxation is probably a physiologic response to gastric distention
, which stimulates mechanical receptors in the fundus.
There were no instances of barotrauma, submucosal injection of jetted gas, gastric distention
, mucosal damage, seeding of blood or debris into the tracheobronchial tree, or tube ignition in any of the 84 cases.
1,4) One of the most common contexts in which it is encountered is in the perioperative period, where it may be due to medications such as opioids and short-acting barbiturates, manipulation of the diaphragm or other organs during surgery, inadequate ventilation, and gastric distention