Herein, we further found that AB23 obviously induced G1 phase
cell cycle arrest in ovarian cancer cells.
At the end of the process, the cells still have the ability to interact with the environment, but remain permanently in the G1 phase
of the cell cycle, not responding to physiologic stimuli for progression in the cycle or for DNA synthesis (LI et al.
Maximal expression of cyclin E was observed during the GO/ G1 phase
, which was higher than that during the S phase (P < 0.
Annonacin, a mono-tetrahydrofuran acetogenin, arrests cancer cells at the G1 phase
and causes cytotoxicity in a Baxand caspase-3-related pathway.
AKAP149 is a novel PP1 specifier required to maintain nuclear envelope integrity in G1 phase
Factors modulating exit from G0 and progression through G1 phase
of the cell cycle are critical in determining overall growth rates of cells.
It was shown that ethanol metabolism slowed the cellular doubling time and increased the fraction of cells in the G1 phase
of the cell cycle; (3) thus impairing progression of cells through the cell cycle and inhibiting cellular replication.
Microspore-containing plant segment from donor plants are harvested and incubated under pre-treatment conditions to maintain microspore at a uninucleate cell cycle G1 phase
Transcription-dependent induction of G1 phase
during the zebrafish midblastula transition.
Using a technique called flow cytometry, her results indicate that treatment with APOPTONE causes growth arrest of the cells in the early cell cycle phase or G1 phase
and also stimulates apoptosis or programmed cell death.
Maintenance of centromeres in somatic cells is tightly cell cycle coupled, as centromeric chromatin assembly is strictly dependent on G1 phase
Previous studies have shown that cell differentiation of ESCs is initiated only in the G1 phase
, attributed to G1- specific properties that contribute to lineage specification.
Analysis of the cell cycle distribution showed that compared with the control, transfection of HepG2 cells with the miR-27a inhibitor significantly increased the number of cells in G1 phase
A high expression of CaM gene can shorten G1 phase
and accelerate cells into S phase, therefore it can shorten cell period and promote cell proliferation (Baitinger et al.
A typical G1 phase
lasts 8-10 hours whereas the embryonic cells spend only a few minutes in G1.