degeneration

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Related to Frontotemporal lobar degeneration: Frontotemporal dementia, frontal lobe dementia
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  • noun

Synonyms for degeneration

Synonyms for degeneration

descent to a lower level or condition

Synonyms for degeneration

the process of declining from a higher to a lower level of effective power or vitality or essential quality

the state of being degenerate in mental or moral qualities

passing from a more complex to a simpler biological form

References in periodicals archive ?
Hippocampal sclerosis of aging is a key Alzheimer's disease mimic: clinical-pathologic correlations and comparisons with both Alzheimer's disease and non-tauopathic frontotemporal lobar degeneration.
It was not until after disease progression in spite of multiple medication trials, and repeated imaging demonstrating the increased brain atrophy, did the diagnosis of frontotemporal lobar degeneration declare itself.
Histopathological changes underlying frontotemporal lobar degeneration with clinicopathological correlation.
A gene called triggering receptor expressed on myeloid cells 2, or TREM2, has been associated with numerous neurodegenerative diseases, such as Alzheimer's disease, Frontotemporal lobar degeneration, Parkinson's disease, and Nasu-Hakola disease.
Frontotemporal lobar degeneration (FTLD) is a rather rare cause of dementia; however, it is a common cause of dementia in individuals younger than 65 years, second only to early-onset Alzheimer disease.
It is also important to consider other causes of dementia including other degenerative disorders (Table 1) such as frontotemporal lobar degeneration (including Pick disease, frontotemporal lobar degeneration with TDP43 and ubiquitin inclusions/motor neuron disease inclusion dementia, and frontotemporal dementia with parkinsonism linked to chromosome 17-tau) and dementia with Lewy bodies, as well as other non-neurodegenerative conditions including vascular dementia, normal pressure hydrocephalus, and CreutzfeldtJakob disease.
It was assumed that a mutation in the progranulin gene, which makes the progranulin protein and supports brain neurons, was sufficient to produce a kind of dementia known as frontotemporal lobar degeneration (FTLD).
Associated disease groups include Alzheimer disease (AD), [2] Parkinson disease, Parkinson disease dementia, and frontotemporal lobar degeneration.