Caregiver burden, health-related quality of life and coping in dementia caregivers: A comparison of frontotemporal dementia
and Alzheimer's disease.
Kertesz A, Munoz D: Relationship between frontotemporal dementia
and corticobasilar and corticobasilar degeneration/Progressive supranuclear palsy.
Mutations in a gene called progranulin (GRN) are commonly associated with frontotemporal dementia
, but GRN mutations in mice do not mimic all the features of the human disorder, which has limited progress in the development of effective treatments.
Dr Doug Brown of the Alzheimer's Society said: "Because frontotemporal dementia
is a rarer form of dementia there's a lack of research.
The agency did, however, determine that amyloid imaging could be useful in excluding Alzheimer's in "narrowly defined and clinically difficult differential diagnoses," such as Alzheimer's versus frontotemporal dementia
Many of the projects we are funding focus on genetics and understanding the risk factors for diseases like Alzheimer's and frontotemporal dementia
They address genetic aspects of hereditary inclusion-body myopathies, animal models, potential treatment, clinical features and epidemiology, the effects of mutations, and inclusion-body myopathy associated with Paget disease and frontotemporal dementia
Chapters begin with anatomy and physiology, then address many aspects of Parkinson's disease, including genetics, environmental factors, pathology, imaging, dementia, psychiatric issues, nonmotor aspects, and therapy, and the management of multiple system atrophy, progressive supranuclear palsy, corticobasal ganglionic degeneration, frontotemporal dementia
, Huntington's disease, dystonia, and other movement disorders like tremors, restless legs syndrome, and psychogenic movement disorders.
26, 2007, issue of the <em>Journal of Neuroscience</em>, demonstrates for the first time a pathological pathway that ultimately results in cell death related to frontotemporal dementia
(FTD) and amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease).
A diagnosis of "probable" AD was made according to the NINCDS-ADRDA criteria (10); the clinical picture of FTLD (including frontotemporal dementia
, semantic dementia, and progressive aphasia) was based on international clinical diagnostic criteria (11).
They all had frontotemporal dementia
, which had impaired their language and intellectual abilities.
By studying the role of Tau in human cells, the company aims to advance a novel therapeutic into the clinic for multiple tauopathies (Alzheimer's disease, Frontotemporal Dementia
, Progressive Supranuclear Palsy (PSP) and others).
About Frontotemporal Dementia
FTD is the most common dementia for adults under the age of 60.
But more than 37 percent of people with frontotemporal dementia
had gotten into legal trouble.
The third global study, TauRx's Phase III clinical trial (Protocol TRx-237-007) in patients with behavioural variant frontotemporal dementia
(bvFTD), continues to recruit subjects, and is on track to complete enrolment by early 2015.