has signed a license agreement with the National Research Council (NRC) of Canada to develop ATI-1701, a vaccine to protect against Francisella tularensis
, a potential bioterrorism agent that causes tularemia, the company said.
Immunization against tularemia: analysis of the effectiveness of live Francisella tularensis
vaccine in prevention of laboratory-acquired tularemia.
Virulence differences among Francisella tularensis
Affiliation to the species Francisella tularensis
was confirmed by amplification of the 17 kDa outer membrane lipoprotein gene fragment (species-specific tul4 gene) as described previously .
This report provides comprehensive information on the therapeutic development for Francisella Tularensis
Infections, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases.
It is the second federal contract awarded to the firm for work in this area and will support Diatherix's development of technologies directed at Francisella tularensis
, Escherichia coli, and Babesia microti.
Serological tests for parasitic and bacterial infections revealed that Tuberculosis, Brucella, Toxocara canis, Leishmania, Entamoeba histolytica, Schistosoma, Borrelia burgdorferi, Francisella tularensis
, Fasciola hepatica were negative.
Tularemia: Informally known as "rabbit fever," this disease is caused by the bacterium Francisella tularensis
This report provides information on the therapeutic development for Francisella Tularensis
Infections, complete with latest updates, and special features on late-stage and discontinued projects.
Clinical presentations of atypical pneumonia are most commonly caused by six organisms: three zoonotic organisms--Chthmydia psittaci (psittacosis), Francisella tularensis
(tularemia), and Coxiella bunzetii (Q fever), and three non-zoonotic pathogens--Chlarnydia pneunzoniae.
The contract includes preclinical efficacy and toxicology studies, clinical studies, manufacturing, and associated regulatory activities for TP-434 as a potential treatment of inhalation-al disease caused by Bacillus anthracis, Francisella tularensis
and Yersinia pestis.
Among the topics are quantitative mass spectrometric approaches, analyzing Francisella tularensis
glycoproteins, the chemical composition and structure of Coxiella burnetii lipopolysaccharides and their role in the diagnosis of Q fever, protein microarrays for antigen discovery, and the proteome analysis of protein expression in bacteria after macrophages have ingested them.
3) Moreover, some infectious agents such as Francisella tularensis
may require specific culture techniques as well as specific safety procedures.
Wayne Jonas and Debra Dillner, in this study, set out to determine the effect of a homeopathic potency of Francisella tularensis
, the bacteria involved in Tularema, on mice exposed to the same organism.
coli O:116 y 0:157, Francisella tularensis
, Salmonella sp.