fibroblast

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  • noun

Words related to fibroblast

a cell from which connective tissue develops

References in periodicals archive ?
These two cell types were observed on the feeder cell layer 2 to 3 days after seeding the blastocysts (Figure 1C and 1D).
A culture system using human foreskin fibroblasts as feeder cells allows production of human embryonic stem cells.
ES cells are differentiated into specified cells by embryoid body (EB) formation and addition of trophic factors, co-culture with feeder cells or others (Assady et al.
In ongoing research, HepaLife says its PICM-19H liver stem cells have demonstrated the crucial ability not only to survive, but also remain functional without feeder cell support.
In work published in the October issue of Nature Biotechnology, Geron scientists have discovered methods to maintain hES cell growth in the absence of direct feeder cell support.
Feeder cells are mouse cells that hold PICM-19 cells in place and provide important molecules for PICM-19 cell growth and maintenance.
Most commonly, the inner cell mass of the blastocyst is mechanically removed and plated onto feeder cells (usually mitotically inactivated mouse fibroblasts), and fed with medium and growth factors until colonies form.
They suggested that presence of serum or feeder cells complicates the culture conditions making them uncontrollable (6).
Schlegel added that they do this rapidly -- within three days of adding the inhibitor and feeder cells, they efficiently generated large numbers of stem-like cells.
LIF is secreted from feeder cells, which provide the basis for cell cultivation.
In addition Zenith introduces their StemQ(R) complete line of mouse embryonic stem (ES) cell lines; primary mouse embryonic fibroblast feeder cells (PMEFs), media and reagents.
The company announced the publication in Cloning and Stem Cells Journal, published on November 20, of an article describing the utilization of umbilical cord blood components to act as feeder cells (part of a cell growth medium) for the growth of undifferentiated embryonic stem cells.
The use of feeder cells in cell culture was first reported by Puck et al.
These feeder cells offer embryonic stem cells a suitable attachment surface and also release largely uncharacterized nutrients into the culture medium that support stem cell growth in the undifferentiated state.
Stem Cells published Geron studies which demonstrated that human embryonic stem cells (hESCs) can be propagated in culture using defined growth factors without the need for feeder cells or media conditioned by feeder cells.